Results 41 to 50 of about 229,787 (259)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A molecularly engineered large-area nanoporous atomically thin graphene membrane for ion separation

Nature Communications
Atomically thin graphene membranes with sub-1-nm pores show promise for ion/molecular separation, osmotic energy generation, and energy storage. Narrowing the pore size distribution and controlling the surface charge are essential to achieve these ...
Ziwen Dai, Pengrui Jin, Shushan Yuan, Jiakuan Yang, Kumar Varoon Agrawal, Huanting Wang   +5 more
doaj   +1 more source

Enhanced pore space analysis by use of μ-CT, MIP, NMR, and SIP [PDF]

Solid Earth, 2018
We investigate the pore space of rock samples with respect to different petrophysical parameters using various methods, which provide data on pore size distributions, including micro computed tomography (μ-CT), mercury intrusion porosimetry (MIP ...
Z. Zhang, S. Kruschwitz, S. Kruschwitz, A. Weller, M. Halisch   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Study of the relationship between hydro-mechanical soil behavior and microstructure of a structured soil

Earth Sciences Research Journal, 2018
Structured soils, such as residual laterites or volcanic ashes, abound in tropical regions. The hydro-mechanical behavior of these soils is clearly related to their structure. New techniques based on microstructural studies constitute a powerful tool for
Manoel Porfirio Cordão Neto, Oisy Hernández, Raydel Lorenzo Reinaldo, Camila Borges, Bernardo Caicedo   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Virtual CT analysis of pore structure in DEM-generated granular media: Application to porous asphalt

Materials & Design
Computed tomography (CT) is widely used to characterise pore structures in granular and porous materials, yet the influence of voxel resolution on quantitative metrics remains insufficiently understood, particularly for DEM-generated assemblies with ...
Zhiyuan Zhang
doaj   +1 more source

Permeability-Selectivity Analysis of Microfiltration and Ultrafiltration Membranes: Effect of Pore Size and Shape Distribution and Membrane Stretching

Membranes, 2016
We present a modeling approach to determine the permeability-selectivity tradeoff for microfiltration and ultrafiltration membranes with a distribution of pore sizes and pore shapes. Using the formulated permeability-selectivity model, the effect of pore
Muhammad Usama Siddiqui, Abul Fazal Muhammad Arif, Salem Bashmal   +2 more
doaj   +1 more source