Results 101 to 110 of about 799,943 (286)

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

open access: yesAdvanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen   +15 more
wiley   +1 more source

[Porous polyethylene implant (Medpor (R)) implant: prospective study of 75 primary implantation procedures]

open access: yes, 2001
Purpose: To examine the incidence of orbital complications in patients who underwent primary placement of a porous polyethylene implant (Medpor(R)) after enucleation.
De Potter, Patrick, Van Acker, E
core  

Orbital pseudotumour masquerading as Wegener’s granulomatosis [PDF]

open access: yes, 2015
A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses.
Fenech, Matthew T., Fenech, Thomas
core  

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Ceramic orbital implant: a study of the efficacy, acceptability and safety of a locally produced hydroxyapatite orbital implant for the anophthalmic socket [PDF]

open access: yes, 2008
A novel locally manufactured and developed porous hydroxyapatite orbital implant has been investigated and found to be as safe as commercially available implants.
Levitz, Mark Lewis
core  

Postcontrast magnetic resonance imaging assessment of porous polyethylene orbital implant (Medpor).

open access: yes, 2000
OBJECTIVE: To evaluate the fibrovascular ingrowth progression within the porous polyethylene orbital implant (Medpor) with serial magnetic resonance imaging (MRI). DESIGN: Prospective, nonrandomized, comparative (self-controlled) trial. PARTICIPANTS: Ten
De Potter, Patrick   +5 more
core   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

open access: yesAdvanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang   +7 more
wiley   +1 more source

Nanowires Reinforce Oriented Macroporous Aerogels for Rapid Uranium Removal from Acidic Radioactive Wastewater

open access: yesAdvanced Science, EarlyView.
A “reinforced concrete” structural aerogel with directional microchannels is engineered for rapid uranium capture. The interconnected architecture enables ultrafast water permeation, and the nanowire reinforcement yields a 70‐fold increase in mechanical strength.
Ze Liu   +8 more
wiley   +1 more source

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