Results 151 to 160 of about 72,390 (265)

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

open access: yesAdvanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez   +8 more
wiley   +1 more source

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

open access: yesAdvanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher   +19 more
wiley   +1 more source

Mild selective photochemical oxidation of an organic sulfide using OxP-polyimide porous polymers as singlet oxygen generators. [PDF]

open access: yesSci Technol Adv Mater
Hynek J   +8 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei   +9 more
wiley   +1 more source

A 3D‐Printed Vascular‐Like Perfusion Tumor‐on‐a‐Chip Recapitulates High‐Grade Breast Cancer With in Vivo‐Relevant Drug Resistance

open access: yesAdvanced Healthcare Materials, EarlyView.
A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee   +3 more
wiley   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

open access: yesAdvanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang   +4 more
wiley   +1 more source

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