Results 101 to 110 of about 269 (192)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Impact of Flow Restrictors on Aerosol Delivery of the Respimat® Soft Mist Inhaler. [PDF]

open access: yesPulm Ther
Fleischhauer M   +6 more
europepmc   +1 more source

Spatially Decoupling Heating and Evaporation for Convection‐Enhanced 3D Solar Evaporation With Continuous Salt Harvesting

open access: yesAdvanced Functional Materials, EarlyView.
An architecture‐enabled bottom‐heated 3D solar convective evaporator spatially decouples photothermal heating from evaporation, triggering natural convection that intensifies sidewall vapour removal and heat transfer. The system achieves significantly enhanced evaporation rates over 2D and conventional 3D designs while confining salt precipitation to ...
Xiaolong Ma   +7 more
wiley   +1 more source

Direct coupling of the human nuclear exosome adaptors NEXT and PAXT with transcription termination and processing machineries. [PDF]

open access: yesNucleic Acids Res
Kuhn CC   +7 more
europepmc   +1 more source

Study on Non-Contact Transportation Technique of Large Glass Sheet for LCDs (In the Case of Restrictor Using Porous Film)

open access: yesProceedings of JSPE Semestrial Meeting, 2012
Tsuno, Hiroaki   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy