Results 201 to 210 of about 41,759 (263)

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Corrigendum to "Effects during the cathode polarization of porous silicon" [Heliyon Volume 10, Issue 15, August 2024, Article e34675]. [PDF]

Heliyon
Yakovtseva V, Volchek S, Bondarenko V, Sayyed MI, Hanafy TA, Trukhanov S, Bondaruk A, Rotkovich A, Silibin MV, Zubar T, Tishkevich D, Trukhanov A.   +11 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Porous silicon and silica carriers for delivery of peptide therapeutics. [PDF]

Drug Deliv Transl Res
Yan J, Siwakoti P, Shaw S, Bose S, Kokil G, Kumeria T.   +5 more
europepmc   +1 more source

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

Advanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li, Changning Bai, Xingkai Zhang, Yusheng Liang, Wei Wu, Dingrui Zhou, Tao Du, Chunjin Wang   +7 more
wiley   +1 more source

Engineered etching and laser treatment of porous silicon for enhanced sensitivity and speed of Pt/n-PSi/Pt UV photodetectors. [PDF]

Nanoscale Adv
Thahe AA, Dahi A, Qaeed MA, Farhat OF, Bakhtiar H, Allam NK.   +5 more
europepmc   +1 more source

Geomag Mimetic Dynamically Reconfigurable POSS Framework Enables Antifatigue Solid Electrolyte Interphases for Lithium Metal Anodes

Advanced Science, EarlyView.
A Geomag‐inspired dynamically reconfigurable POSS framework is constructed to form an antifatigue solid electrolyte interphase (SEI) for lithium metal anodes. The rigid POSS nanocages and reversible hydrogen‐bonded junctions enable adaptive stress dissipation and stable Li+ transport during repeated plating/stripping, thereby suppressing dendrite ...
Tianyi Wang, Wei Gu, Yu Liu, Di He, Zairan Xiao, Zixia Lin, Tao Huang, Jiabao Li, Hui Chong, Yaojie Lei, Xiaobo Zheng, Bing Sun, Guoxiu Wang, Chengyin Wang   +13 more
wiley   +1 more source

Photoelectrocatalytic Reduction of CO 2 to Formate Using Immobilized Molecular Manganese Catalysts on Oxidized Porous Silicon. [PDF]

Chem
Hong YH, Jia X, Stewart-Jones E, Kumar A, Wedal JC, Alvarez-Hernandez JL, Donley CL, Gang A, Gibson NJ, Hazari N, Houck M, Jeon S, Kim J, Koh H, Mayer JM, Mercado BQ, Nedzbala HS, Piekut N, Quist C, Stach E, Zhang Y.   +20 more
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Development of Porous Silicon(Si) Anode Through Magnesiothermic Reduction of Mesoporous Silica(SiO₂) Aerogel for All-Solid-State Lithium-Ion Batteries. [PDF]

Gels
Kapadnis PS, Kim K, Nam K, Kim Y, Park HH, Hwang H.   +5 more
europepmc   +1 more source