Results 1 to 10 of about 1,932 (163)
Porphyria cutanea tarda and Sjogren's syndrome [PDF]
Anais Brasileiros de Dermatologia, 2014 Porphyria cutanea tarda is prevalent in connective tissue disease, common in systemic lupus erythematosus. However, the co-existence of primary sjogren's syndrome and porphyria cutanea tarda is rare and poses diagnostic and therapeutic challenges.
Su Fang +4 more
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Porphyria cutanea tarda exacerbation as a paraneoplastic syndrome in vaginal cancer resolved with chemoradiation [PDF]
Gynecologic Oncology Reports, 2021 Porphyria Cutanea Tarda (PCT) is a rare paraneoplastic syndrome. The effects of therapeutic ionizing radiation in patients with PCT are not well understood.
Sarah Z. Hazell +2 more
doaj +2 more sources
Porphyria cutanea tarda: a case report [PDF]
Journal of Medical Case Reports, 2019 Background The porphyrias are a rare group of metabolic disorders that can either be inherited or acquired. Along the heme biosynthetic pathway, porphyrias can manifest with neurovisceral and/or cutaneous symptoms, depending on the defective enzyme ...
Hanife Usta Atmaca, Feray Akbas
doaj +2 more sources
Case Report: Treatment of porphyria cutanea tarda with low dose hydroxychloroquine [version 1; peer review: 1 approved, 2 approved with reservations] [PDF]
F1000Research, 2022 Background: Porphyria cutanea tarda (PCT) is a complex metabolic disease resulting from altered activity of the enzyme uroporphyrinogen decarboxylase (UROD) in the liver resulting in accumulation of uroporphyrin.
Alexander Nirenberg +2 more
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Secondary hemosiderosis presented by porphyria cutanea tarda in a kidney dialysis patient: A case report [PDF]
SAGE Open Medical Case Reports, 2020 A 68-year-old woman with chronic kidney disease receiving dialysis and iron supplementation presented to our hospital with painful blisters, fragile skin, and changes to skin pigmentation on the dorsal side of both upper and lower limbs.
Farjah H AlGahtani +2 more
doaj +2 more sources
Journal of Osteopathic Medicine, 2016 Porphyria cutanea tara (PCT) has a prevelance of about 40 new diagnoses per 1 million people per year and is the most frequently occurring type of porphyria worldwide. Inhibition of the uroporphyrinogen decarboxylase (UROD) is the main cause of the disease, which can be the result of a heterozygous or homozygous mutation of the UROD gene; however ...
Eric M, Neverman, Rochelle, Parker
exaly +5 more sources
Porphyria cutanea tarda in a HIV- positive patient [PDF]
Anais Brasileiros de Dermatologia, 2016 : This is a case report about Porphyria cutanea tarda (PCT) and its relationship with the infection caused by the human immunodeficiency virus (HIV). Cutaneous porphyria is an illness caused by enzymatic modification that results in partial deficiency of
Valéria Aparecida Zanela Franzon +3 more
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Ugeskrift for LægerPorphyria cutanea tarda (PCT) is caused by decreased activity of uroporphyrinogen decarboxylase (UROD) due to various susceptibility factors, here among pathogenic variants in UROD and the presence of iron overload. Porphyrins are sensitive to light and cause cutaneous symptoms in the form of blisters and ulcers on sun-exposed skin.
Sathe NC, Killeen RB, Bhatt H.
europepmc +6 more sources
Porphyria cutanea tarda and systemic lupus erythematosus: a case report [PDF]
Journal of Medical Case ReportsBackground Systemic lupus erythematosus is characterized by multiorgan involvement and the presence of autoantibodies. Porphyria cutanea tarda is a condition that affects the liver and skin by downregulating and inhibiting the enzyme uroporphyrinogen ...
Jairo Cajamarca-Baron +5 more
doaj +2 more sources
Early presentation of adult-onset conditions: A dual diagnosis of hereditary hemochromatosis and porphyria cutanea tarda [PDF]
Molecular Genetics and Metabolism Reports, 2020 Asymptomatic aminotransferase elevation has a broad differential in the pediatric population. We report an 11-year old male with a history of urine discoloration found to have persistently elevated aminotransferases.
Alanna Strong +2 more
doaj +2 more sources