Results 61 to 70 of about 23,339 (176)
Skin changes in chronic kidney disease
Przegląd Dermatologiczny, 2017 Chronic kidney disease causes skin changes which may sometimes be the first sign of kidney failure. Specific skin changes include acquired perforating dermatosis, porphyria cutanea tarda, pseudoporphyria, calcinosis and nephrogenic systemic fibrosis. The
Joanna M. Przepiórka-Kosińska +4 more
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The management of porphyria cutanea tarda
Clinical and Experimental Dermatology, 2001 AbstractPorphyria cutanea tarda (PCT), the commonest of all porphyrias, is usually characterized by blisters and fragility of skin in light-exposed areas. It can be clinically indistinguishable from other disorders including variegate porphyria and the diagnosis can only be made by rigorous biochemical analysis.
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Role of Vitamin C in Skin Diseases
Frontiers in Physiology, 2018 Vitamin C (ascorbic acid) plays an important role in maintaining skin health and can promote the differentiation of keratinocytes and decrease melanin synthesis, leading to antioxidant protection against UV-induced photodamage.
Kaiqin Wang +5 more
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Pregnancy and porphyria cutanea tarda
Acta Dermato-Venereologica, 1984 A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy which was normal. Her hormone analytic
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Treatment options in acute porphyria, porphyria cutanea tarda, and erythropoietic protoporphyria
, 2007 The porphyrias are a group of uncommon metabolic diseases caused by enzyme deficiencies within heme biosynthesis that lead to neurotoxic or phototoxic heme precursor accumulation. There are four acute porphyrias characterized by neuropsychiatric symptoms:
Harper, P,, Wahlin, S,
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A case of porphyria cutanea tarda in the setting of hepatitis C infection and tobacco usage [PDF]
, 2019 Porphyria cutanea tarda (PCT) is the most common type of porphyria, presenting in middle-aged patients with a photodistributed vesiculobullous eruption, milia, and scars.
Chen, L +4 more
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Iron overload in porphyria cutanea tarda
Haematologica, 1999 BACKGROUND AND OBJECTIVE: Porphyria cutanea tarda (PCT) is a disorder of porphyrin metabolism associated with decreased activity of uroporphyrinogen decarboxylase (URO-D) in the liver. The relevance of iron in the pathogenesis of PCT is well established:
M Sampietro, G Fiorelli, S Fargion
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Sporadic porphyria cutanea tarda due to haemochromatosis [PDF]
, 2006 Haemochromatosis is a hereditary iron-overload syndrome caused by increased intestinal iron absorption and characterised by accumulation of potentially toxic iron in the tissues.
Dees, A., Geus, H.R.H. (Hilde) de
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Clinically Important Features of Porphyrin and Heme Metabolism and the Porphyrias
Metabolites, 2014 Heme, like chlorophyll, is a primordial molecule and is one of the fundamental pigments of life. Disorders of normal heme synthesis may cause human diseases, including certain anemias (X-linked sideroblastic anemias) and porphyrias.
Siddesh Besur +3 more
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Lack of association between porphyria cutanea tarda andalpha 1-antitrypsin deficiency
, 1996 Objective: To determine whether alpha(1)-antitrypsin deficiency is involved in the pathogenesis of chronic liver disease in patients with porphyria cutanea tarda and in their recently described high prevalence of hepatitis C virus infection.
A.L. Fracanzani +8 more
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