Results 31 to 40 of about 726,100 (301)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The Ambidextrous Role of Inland Terminals in Enhancing Port–Hinterland Connectivity

Logistics
Background: The operational roles of ports are deeply intertwined with the development of their surrounding hinterlands, indicating that their relationship is mutually dependent and interactive.
Tomislav Rožić, Diana Božić, Ivona Bajor, Berislav Andrlić   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Choisir sa transition : modernisation écologique et gouvernance multi-niveaux dans l’estuaire de la Loire

Développement Durable et Territoires
What ecological transitions are being implemented in port regions, and why? The Loire Estuary aims to become an international reference for energy transition, driven by the positioning of the Grand Port Maritime of Nantes Saint-Nazaire on renewable ...
Annabelle Duval
doaj   +1 more source

Samanian and imitation policy from Sassanian’s administrative structures [PDF]

پژوهش‌های تاریخی ایران و اسلام, 2017
With the collapse of the Sassanid Empire and the arrival of Islam in Iran and the establishment of Islamic Caliphate by Umavyian and Abassian (Umavyid and Abassid) as well as the attempts of the Iranian semi-independent governments such as Taherian and ...
سامان ستاریان،, هوشنگ خسرو بیگی،, جمشید نوروزی،, سید حسن قریشی،   +3 more
doaj   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Evaluation and Justification of RFID Implementation In IRAN Commercial Port's Container Supply Chain (Case Study: Bushehr Port) [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2011
Simultaneous with port's development and complexity in transportation processes, a number of problems have occurred in global supply chain. Nowadays, new technologies are used as a flexible solution to control quality of services and manage port's ...
Shahriar Mohammadi, Sedigheh Ardast
doaj  

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

A Creative Approach to the Port-City Relationship: The Case of Zones Portuaires in Genoa

European Journal of Creative Practices in Cities and Landscapes, 2021
One of the goals of 2030 AIVP Agenda is to strengthen port-city relationship by “promoting and capitalising on the specific culture and identity of port cities and allowing residents to develop a sense of pride and flourish as part of a city port ...
Maria Elena Buslacchi, Maria Pina Usai
doaj   +1 more source