Results 191 to 200 of about 176,647 (307)

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

open access: yesAdvanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan   +5 more
wiley   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South-South region of Nigeria: The effect of genetics, environment and lifestyle. [PDF]

open access: yesDiabet Med
Chinenye S   +18 more
europepmc   +1 more source

Polymer‐Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring

open access: yesAdvanced Science, EarlyView.
A monolithic integrated photonic chip simultaneously measures blood glucose, pressure, temperature, ECG, and sweat glucose. Combining multiple Bragg grating sensors, Mach–Zehnder modulators, and an on–‐chip demodulation unit, this compact chip (1 cm × 0.5 cm) offers robust multiparameter detection.
Xiaolin Li   +11 more
wiley   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

open access: yesAdvanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim   +9 more
wiley   +1 more source

Flexibility in Port Selection: A Quantitative Approach Using Floating Stocks

open access: yes
Ports provide a number of logistical choices concerning storage, onward transport, and postponement. We investigatethe routing flexibility offered by ports with a central location with respect to the hinterland.
Dekker, R., Asperen, E. van
core  

Interacting Parallel Fluidic Hysterons

open access: yesAdvanced Science, EarlyView.
The parallel coupling of fluidic hysterons is introduced, establishing advanced functionalities in inflatable soft systems. A pressure–volume framework reveals how preset volumes Δv∗${\Delta }v^*$ tune nonlinear interactions between hysterons and actuation sequences without changing architecture. Experiments validate the predictions, opening new routes
Katrien Stinissen   +2 more
wiley   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

open access: yesAdvanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau   +22 more
wiley   +1 more source

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