Results 1 to 10 of about 114,857 (246)

Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy [PDF]

open access: goldJournal of Immunology Research, 2021
Liver diseases, including cirrhosis, viral hepatitis, and hepatocellular carcinoma, account for approximately two million annual deaths worldwide.
Martín Muñoz-Ortega   +7 more
doaj   +6 more sources

External Hemorrhage from a Portacaval Anastomosis in a Patient with Liver Cirrhosis [PDF]

open access: goldCase Reports in Hepatology, 2014
Variceal bleeding is the major complication of portal hypertension in patients with liver cirrhosis. Hemorrhage mainly occurs in gastrointestinal lumen. Extraluminal hemorrhages are quite rare, such as intraperitoneal hemorrhages.
Murat Biyik   +8 more
doaj   +5 more sources

Reduced Liver Lipid Peroxidation in Subcellular Fractions Is Associated with a Hypometabolic State in Rats with Portacaval Anastomosis. [PDF]

open access: hybridOxid Med Cell Longev, 2019
A surgical connection between portal and inferior cava veins was performed to generate an experimental model of high circulating ammonium and hepatic hypofunctioning.
Vázquez-Martínez O   +8 more
europepmc   +5 more sources

Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis. [PDF]

open access: hybridWorld J Gastroenterol, 2006
AIM To assess whether portacaval anastomosis (PCA) in rats affects the protein expression and/or activity of glutaminase in kidneys, intestines and in three brain areas of cortex, basal ganglia and cerebellum and to explain the neurological alterations ...
Romero-Gomez M   +8 more
europepmc   +4 more sources

Portacaval anastomosis promotes fragmentation of mitochondrial network in the cerebellum of male rats. [PDF]

open access: hybridMetab Brain Dis
Portacaval anastomosis (PCA) is a model for hypometabolic liver dysfunction. Spongiform neurodegeneration has been detected in the cerebellum of PCA rats 13 weeks after surgery. This report characterizes the damage associated with spongiform degeneration
López-Cervantes M   +7 more
europepmc   +4 more sources

Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence [PDF]

open access: yesJCI Insight, 2021
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including senescence induction. During dysregulated ammonia metabolism, which occurs in chronic diseases, skeletal muscle becomes a major organ for nonhepatocyte ammonia ...
Avinash Kumar   +15 more
doaj   +2 more sources

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