Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy [PDF]
Liver diseases, including cirrhosis, viral hepatitis, and hepatocellular carcinoma, account for approximately two million annual deaths worldwide.
Martín Muñoz-Ortega +7 more
doaj +6 more sources
External Hemorrhage from a Portacaval Anastomosis in a Patient with Liver Cirrhosis [PDF]
Variceal bleeding is the major complication of portal hypertension in patients with liver cirrhosis. Hemorrhage mainly occurs in gastrointestinal lumen. Extraluminal hemorrhages are quite rare, such as intraperitoneal hemorrhages.
Murat Biyik +8 more
doaj +5 more sources
Reduced Liver Lipid Peroxidation in Subcellular Fractions Is Associated with a Hypometabolic State in Rats with Portacaval Anastomosis. [PDF]
A surgical connection between portal and inferior cava veins was performed to generate an experimental model of high circulating ammonium and hepatic hypofunctioning.
Vázquez-Martínez O +8 more
europepmc +5 more sources
Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis. [PDF]
AIM To assess whether portacaval anastomosis (PCA) in rats affects the protein expression and/or activity of glutaminase in kidneys, intestines and in three brain areas of cortex, basal ganglia and cerebellum and to explain the neurological alterations ...
Romero-Gomez M +8 more
europepmc +4 more sources
Portacaval anastomosis promotes fragmentation of mitochondrial network in the cerebellum of male rats. [PDF]
Portacaval anastomosis (PCA) is a model for hypometabolic liver dysfunction. Spongiform neurodegeneration has been detected in the cerebellum of PCA rats 13 weeks after surgery. This report characterizes the damage associated with spongiform degeneration
López-Cervantes M +7 more
europepmc +4 more sources
Cholesterol homeostasis in the rat with a portacaval anastomosis. [PDF]
Proia A +3 more
europepmc +4 more sources
Fifteen-year survival following portacaval anastomosis. [PDF]
Kirkham JS, Tanner NC.
europepmc +5 more sources
Treatment of familial hypercholesterolemia by portacaval anastomosis: effect on cholesterol metabolism and pool sizes. [PDF]
McNamara DJ +7 more
europepmc +4 more sources
Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence [PDF]
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including senescence induction. During dysregulated ammonia metabolism, which occurs in chronic diseases, skeletal muscle becomes a major organ for nonhepatocyte ammonia ...
Avinash Kumar +15 more
doaj +2 more sources

