Results 21 to 30 of about 1,319 (96)
Sarcopenia is a common complication of cirrhosis with a negative impact on posttransplant outcome, health‐related quality of life (HRQOL), and patient survival. Studies in experimental animals and in patients demonstrate that ammonia is directly implicated in the pathogenesis of sarcopenia in cirrhosis via mechanisms involving increased expression of ...
Roger F. Butterworth, Quirino Lai
wiley +1 more source
We aimed to evaluate the safety and efficacy of low doses of anti‐T‐lymphocyte globulin (ATG)‐based immunosuppression in preserving renal function and preventing liver rejection in liver transplant (LT) recipients with pretransplant renal dysfunction. We designed a prospective single‐center cohort study analyzing patients with pre‐LT renal dysfunction ...
Cristina Dopazo+8 more
wiley +1 more source
Establishment of a Novel Simplified Surgical Model of Acute Liver Failure in the Cynomolgus Monkey
Models using large animals that are suitable for studying artificial liver support system (ALSS) are urgently needed. Presently available acute liver failure (ALF) models mainly involve pigs or dogs. Establishment of current surgical ALF models (hepatectomy/devascularization) requires either very good surgical skills or multistep processes—even ...
Lei Cai+11 more
wiley +1 more source
The effects of portacaval shunt upon hepatic cholesterol synthesis and cyclic AMP in dogs and baboons [PDF]
Hepatic cholesterol synthesis, hepatic cyclic AMP, and portal and peripheral insulin and glucagon levels were investigated in nine dogs and three baboons after complete portacaval shunt.
Benichou, J+3 more
core
Loss of liver mass and ischemia/reperfusion injury (IRI) are major contributors to postresectional liver failure and small‐for‐size syndrome. Mesenchymal stromal cell‐ (MSC‐) secreted factors are described to stimulate regeneration after partial hepatectomy.
Suomi M. G. Fouraschen+9 more
wiley +1 more source
A systematic review of the literature was performed to analyze the association between portal vein thrombosis (PVT) and survival in non‐liver‐transplant patients with liver cirrhosis. PubMed, EMBASE, and Cochrane Library databases were searched for all relevant papers which evaluated the prognostic value of PVT in predicting the survival of liver ...
Xingshun Qi+6 more
wiley +1 more source
The eck fistula in animals and humans [PDF]
In all species so far studied, including man, portacaval shunt causes the same changes in liver morphology, including hepatocyte atrophy, fatty infiltration, deglycogenation, depletion and disorganization of the rough endoplasmic reticulum (RER) and its ...
Aagenaes+269 more
core +1 more source
Management of gastroesophageal varices in cirrhotic patients: current status and future directions
Bleeding from gastroesophageal varices (GEV) is a serious event in cirrhotic patients and can cause death. According to the explosion theory, progressive portal hypertension is the primary mechanism underlying variceal bleeding.
Nobuyuki Toshikuni+2 more
doaj
Morphologic and Biochemical Changes in Dogs After Portacaval Shunt Plus Bile Fistula or Ileal Bypass: Failure of Bile Fistula or Ileal Bypass to Prevent Hepatocyte Atrophy [PDF]
External biliary fistula (BF) or ileal bypass (IB) was performed in dogs at the time of or 2 weeks after portacaval shunt (PCS). The pathologic changes in the dog livers 2 to 4 weeks later were compared to those caused by PCS alone.
Francavilla, A+7 more
core +1 more source
Portacaval shunt for glycogen storage disease and hyperlipidaemia. [PDF]
Complete portacaval shunt was used to treat 10 patients with glycogen storage disease. A favourable effect was noted on body growth and a number of metabolic abnormalities.
Benichou, J+3 more
core