Results 111 to 120 of about 89,230 (317)
Hemodynamic assessment of pulmonary hypertension in mice: a model based analysis of the disease mechanism [PDF]
arXiv, 2017 This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the main pulmonary artery for 7 control mice with normal pulmonary function and 5 hypertensive mice with hypoxia induced ...
arxiv
"Primary" Pulmonary Hypertension with Coexisting Portal Hypertension [PDF]
, 1960 Richard L. Naeye
openalex +1 more source
Improved Esophageal Varices Assessment from Non-Contrast CT Scans [PDF]
arXivEsophageal varices (EV), a serious health concern resulting from portal hypertension, are traditionally diagnosed through invasive endoscopic procedures. Despite non-contrast computed tomography (NC-CT) imaging being a less expensive and non-invasive imaging modality, it has yet to gain full acceptance as a primary clinical diagnostic tool for EV ...
arxiv
The Pathology and Management of Portal Hypertension [PDF]
, 1960 NULL AUTHOR_ID
openalex +2 more sources
End-Stage Liver Disease Comorbidities in Patients Awaiting Transplantation: Identification and Impact on Liver Transplant Survival [PDF]
arXivEnd-Stage Liver Disease (ESLD), a complex condition, has high rates of co-occurring comorbidities affecting multiple organ systems. There is no clear evidence-based practice (EBP) guidelines addressing the progression of comorbidities in ESLD patients awaiting liver transplantation (LT) and their impact on survival, both pre- and post-transplant.
arxiv
A comparative analysis of metamodels for lumped cardiovascular models, and pipeline for sensitivity analysis, parameter estimation, and uncertainty quantification [PDF]
arXivZero-dimensional (0D) cardiovascular models are reduced-order models used to study global circulation dynamics and transport. They provide estimates of biomarkers (such as pressure, flow rates, and concentrations) for surgery planning and boundary conditions for high-fidelity 3D models.
arxiv
PH&C: A new journey in Liverland
Portal Hypertension & Cirrhosis, 2022 Xiaolong Qi
doaj +1 more source
Medicine Bulletin, EarlyView.Recent clinical trials transplanted gene‐edited pig hearts, kidneys, and a liver into eight human patients, demonstrating xenotransplantation's potential to address organ shortages. While showing promise, outcomes varied, highlighting key challenges including immune rejection and managing patient comorbidities, requiring further optimization.
Lisha Mou, Zuhui Pu, David K. C. Cooper
wiley +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Neuroprotection, EarlyView.Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source
Obesity, EarlyView.Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian +17 more
wiley +1 more source