Results 171 to 180 of about 1,183,167 (309)

Clinical Features of Portal Hypertension and Their Prognostic Implications in Patients With Autoimmune Hepatitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Features of clinically significant portal hypertension (CSPH) in patients with autoimmune hepatitis indicate a substantial risk for decompensation and impaired transplant‐free survival. Non‐invasive risk prediction based on liver stiffness measurement ≥ 15 kPa and/or thrombocytopenia (< 150 G/L) serves as a valuable surrogate to identify patients at ...
Lukas Burghart, Sonja Treiber, David Bauer, Emina Halilbasic, Benedikt S. Hofer, Mattias Mandorfer, Michael Gschwantler, Caroline Schwarz, Michael Trauner, Thomas Reiberger, Albert F. Stättermayer   +10 more
wiley   +1 more source

Clinical significance of transjugular intrahepatic portosystemic shunting for hepatocellular carcinoma complicated with portal hypertension. [PDF]

J Gastrointest Oncol
Dai F, Pan C, Xu C, Yao Y, Su M, Ren J, Qiu Z, Capasso M, Zhang X.   +8 more
europepmc   +1 more source

Prediction of Hepatocellular Carcinoma and Other Liver‐Related Events in Chronic Hepatitis B Patients With Metabolic Dysfunction or Metabolic Dysfunction‐Associated Steatotic Liver Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
This study evaluated the performance of the PAGE‐B score in HCC risk among CHB patients with metabolic dysfunction or MASLD. The PAGE‐B score effectively stratified HCC risk in both MASLD and non‐MASLD patients, especially in those without cirrhosis, where low scores were linked to negligible 5‐year HCC risk. ABSTRACT Introduction Metabolic dysfunction
Lesley A. Patmore, Ivana Carey, Jordan J. Feld, Willem P. Brouwer, Keyur Patel, Maria Buti, Pieter Honkoop, Douwe F. Postma, Hans Blokzijl, Özgur. M. Koc, Eva van Oorschot, Kosh Agarwal, Marc van der Valk, Faydra I. Lieveld, Mai Kilany, Matthijs Kramer, Joep de Bruijne, Mark A. A. Claassen, Bettina E. Hansen, Robert A. de Man, Harry L. A. Janssen, R. Bart Takkenberg, Milan J. Sonneveld   +22 more
wiley   +1 more source

Partial splenectomy and pericardial devascularization for symptomatic patients with portal hypertension: a single-center retrospective study. [PDF]

BMC Surg
Zhang Y, Wang S, Yang J, Bu J, Liang F.
europepmc   +1 more source

Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, EarlyView.
In a multi‐centre study of obeticholic acid in primary biliary cholangitis, 45% discontinued the drug over 4 years, with 11% moving to combination therapy (fibrates). Of those continuing, response rates increased from 37% (1 year) to 55% (4 years). Non‐response at 12 months and cirrhosis were independent predictors of liver‐related events.
Nadir Abbas, Rachel Smith, Ellina Lytvyak, Miki Scaravaglio, Neil Halliday, Amal Almahroos, Nadia Eden, Diane Lloyd‐Madden, Sanchit Sharma, James Ferguson, Jessica K. Dyson, Douglas Thorburn, David Jones, Aldo J. Montano‐Loza, Marco Carbone, Pietro Invernizzi, George Mells, Emma L. Culver, Palak J. Trivedi   +18 more
wiley   +1 more source

Non-Invasive Stratification of Portal Hypertension in Patients With BCR::ABL1-Negative Myeloproliferative Neoplasms. [PDF]

Liver Int
Balcar L, Degenfeld-Schonburg L, Hopp C, Kramer G, Graf I, Simonis L, Sillaber C, Kalteis S, Gisslinger H, Meischl T, Stättermayer AF, Mandorfer M, Mitterbauer-Hohendanner G, Reiberger T, Trauner M, Scheiner B, Krauth MT, Semmler G.   +17 more
europepmc   +1 more source

Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: The “Anticipate” study

Hepatology, 2016
J. Abraldes, C. Bureau, H. Stefanescu, S. Augustin, M. Ney, H. Blasco, B. Procopeț, J. Bosch, J. Genescà, A. Berzigotti   +9 more
semanticscholar   +1 more source

Research Communication: The Cumulated Spontaneous Portosystemic Shunts (SPSS) Area Decreases After TIPS and Impacts on Prognosis

Alimentary Pharmacology &Therapeutics, EarlyView.
This study shows that both the total SPSS area and the cumulative SPSS diameter decrease significantly and persistently after TIPS placement, whereas the total shunt diameter increases slightly and the total shunt area remains stable. The relative change in SPSS area serves as an independent predictor of mortality. ABSTRACT We evaluated the dynamics of
Marlene Hintersteininger, Theresa Müllner‐Bucsics, Susanna Riegler, Nina Dominik, Georg Kramer, Christian Sebesta, Paul Thöne, Ulrika Asenbaum, Lukas Reider, Maria Schoder, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Lukas Hartl, Katharina Lampichler   +14 more
wiley   +1 more source

Distinctive Clinical Features of Portal Hypertension in Children with Portal Vein Thrombosis Following Liver Transplantation. [PDF]

Biomedicines
Sansotta N, Di Giorgio A, Colusso MM, Salvi M, Marra P, Pinelli D, Carobbio A, D'Antiga L.   +7 more
europepmc   +1 more source

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

Alimentary Pharmacology &Therapeutics, EarlyView.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang, Jinghua Cui, Yixin Hou, Lining Guo, Hai Li, Guiqin Zhou, Xiaojing Wang, Bingbing Zhu, Ke Shi, Yi Zhang, Yufei Bi, Yanqiu Li, Lina Sun, Ying Feng, Jing Yuan, Xianbo Wang   +15 more
wiley   +1 more source