NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li+14 more
wiley +1 more source
Transjugular Liver Biopsy for Histological Diagnosis of Refractory Ascites and Evaluation of Portal Hypertension. [PDF]
Ishikawa T+8 more
europepmc +1 more source
Serious adverse events associated with bowel preparation for colonoscopy in Japan: Systematic review
Objectives Bowel preparation for colonoscopy can lead to serious adverse events (AEs), raising significant safety concerns in colorectal cancer (CRC) screening. A systematic review of these serious AEs in Japan was performed to explore potential management strategies.
Toshihiro Tadano+8 more
wiley +1 more source
Dual Portal Hypertension in Hepatic Tuberculosis: A Case Report. [PDF]
Joseph A+3 more
europepmc +1 more source
Abstract Aims Despite several modifiable risk factors for dementia being identified, diet is often excluded from consideration due to insufficient evidence. Although various healthy dietary indices have been associated with improved health outcomes, their link to dementia risk remains unclear.
Fernanda Carrasco‐Marín+18 more
wiley +1 more source
Rethinking portal hypertension in hepatocellular carcinoma resection: a gradient of risk beyond black and white. [PDF]
Pereyra D, Starlinger P.
europepmc +1 more source
Causalgenesis of liver fibrosis accompanied with portal hypertension.
Toshio Shikata+2 more
openalex +2 more sources
Higher plasma dicarbonyl levels are associated with liver fibrosis in obese individuals
Abstract Introduction Methylglyoxal (MGO) is a very reactive compound that modifies proteins, forming advanced glycation end products (AGEs) and activating inflammatory pathways. Elevated MGO levels have been linked to various diseases, including type 2 diabetes and atherosclerosis. However, the role of MGO and other glycating agents in the progression
Oluwatomisono I. Akinrimisi+12 more
wiley +1 more source
Case Report: Partial Splenic Artery Embolization for the Treatment of Painful Splenomegaly Secondary to Noncirrhotic Portal Hypertension. [PDF]
Kratzer L+4 more
europepmc +1 more source