Results 111 to 120 of about 431,045 (348)
Antioxidant effect of N-acetylcysteine on prehepatic portal hypertensive gastropathy in rats
Annals of Hepatology, 2014 Background. Portal hypertension is a clinical syndrome associated with the development of a hyperdynamic circulation and gastroesophageal varices.Aim. To evaluate the antioxidant effect of N-acetylcysteine on portal hypertensive rats.Material and methods.
Francielli Licks, M.sc. +5 more
doaj +1 more source
Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
, 2010 Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core +1 more source
Multiple acquired portosystemic shunts in a cat secondary to chronic diaphragmatic rupture [PDF]
, 2015 A cat with a chronic diaphragmatic rupture presented with neurological signs, including twitching and focal seizures. Blood ammonia level was markedly elevated and therefore neurological signs were thought to be related to hepatic encephalopathy ...
Birchard SJ +3 more
core +3 more sources
Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis
Advanced Science, EarlyView.Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park +5 more
wiley +1 more source
Pharmacological Modulation of Liver and Spleen Stiffness in a Cirrhotic Rat Model
Hepatic Medicine: Evidence and ResearchOmar Elshaarawy,1– 3 Shami Hasan M Alquzi,1 Felix Piecha,1,4 Vanessa Rausch,1 Johannes Mueller,1 Sebastian Mueller1 1Center for Alcohol Research, University of Heidelberg, Heidelberg, BW, Germany; 2Department of Gastroenterology, Liver Unit, Liverpool ...
Elshaarawy O +5 more
doaj
The organizational dynamics enabling patient portal impacts upon organizational performance and patient health: a qualitative study of Kaiser Permanente. [PDF]
, 2015 BackgroundPatient portals may lead to enhanced disease management, health plan retention, changes in channel utilization, and lower environmental waste.
de Bont, Antoinette +4 more
core +3 more sources
Advanced Science, EarlyView.ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang +17 more
wiley +1 more source
Gut and Liver, 2007 Background/Aims: Propranolol can prevent variceal bleeding by ameliorating portal hypertension. We conducted this study to determine the effect of propranolol on portal hypertension and the optimal required dose in Korean cirrhotic patients.
doaj +1 more source
BMC Surgery, 2019 Aim To investigate clinical efficacy of transjugular intrahepatic portal shunt (TIPS) for the treatment of cirrhotic portal hypertension. Methods 71 cases of patients with cirrhotic portal hypertension and esophageal and gastric variceal bleeding ...
Yun Chen, Hanyu Qiu, Xiaomei Zhang
doaj +1 more source
Advanced Science, EarlyView.Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma +12 more
wiley +1 more source