Results 121 to 130 of about 431,045 (348)

Persistent varices in cured patients: Understanding the role of hepatic venous pressure gradient

JHEP Reports
Background & Aims: Etiologic factor removal (ER) drives recompensation and improves portal hypertension in cirrhosis. Esophageal varices (EV) and portosystemic shunts (PSS) have been found in patients despite hepatic venous pressure gradient (HVPG ...
Pol Olivas, Alexandre Soler-Perromat, Luis Tellez, José Antonio Carrión, Edilmar Alvarado-Tapias, José Ferrusquía-Acosta, Sabela Lens, Antonio Guerrero, Ángeles Falgà, Pamela Vizcarra, Lara Orts, Valeria Perez-Campuzano, Sarah Shalaby, Sonia Torres, Anna Baiges, Fanny Turon, Juan Carlos García-Pagán, Ángeles García-Criado, Virginia Hernández-Gea   +18 more
doaj   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Portosystemic collateral pathways and interventions in portal hypertension

Gastrointestinal Intervention, 2018
Pathologic increase in portal pressure can be caused by increased resistance to blood flow at the level of the portal vein (pre-hepatic), hepatic sinusoids (hepatic) or hepatovenous outflow (post-hepatic).
Murad Feroz Bandali, Anirudh Mirakhur
doaj   +1 more source

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris, Belzer F O, Denmark S W, Greenway C V, Guy Lebeau, Hoffmann R M, Jamieson N V, Katsuhiko Yanaga, Leonard Makowka, Mitsuo Shimada, Moore F D, Ruey Rong Hwang, Saburo Kakizoe, Starzl T E, Starzl T E, Starzl T E, Thomas E. Starzl, Williams J W   +17 more
core   +1 more source

Prognostic value of early measurements of portal pressure in acute variceal bleeding [PDF]

, 1999
Eduardo Moitinho, Àngels Escorsell, Juan Carlos Bandi, Joan–Manuel Salmerón, Juan Carlos García‐Pagán, Juan Rodés, Jaime Bosch   +6 more
openalex   +1 more source

Hump‐Shaped Relationship Between Microbial Carbon Use‐Efficiency and Soil Organic Carbon in Alpine Grasslands

Advanced Science, EarlyView.
On the Qinghai–Tibetan Plateau, microbial carbon use efficiency (CUE) peaks at intermediate soil organic carbon levels and declines thereafter. In carbon‐rich soils, the formation of stable mineral‐associated organic carbon is decoupled from microbial CUE.
Yuting Wang, Yongneng Wei, Gangsheng Wang, Yang Ruan, Ling Li, Xiang Liu, Yunfeng Yang, Qirong Shen, Ning Ling   +8 more
wiley   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

A Robust Solar Evaporator with Hierarchical Architecture for Ultrahigh Efficiency and Large‐Scale Zero‐Liquid‐Discharge Desalination

Advanced Science, EarlyView.
This study presents a low‐carbon footprint, robust 3D (three‐dimensional) evaporator featuring multi‐level low‐tortuosity channels for highly efficient desalination. It achieves an outstanding average evaporation rate of 8.1 kg m−2 h−1, salt collection rate of 1.95 kg m−2 h−1, and durability in high‐salinity brine.
Lili Sun, Ning Wang, Ning Hu, Yongyun Zhao, Libin Zhao, Wenbo Chen   +5 more
wiley   +1 more source

On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs

Angewandte Chemie, EarlyView.
The nature of ‘improper’ hydrogen bonds is explored in FnC─H⋯X systems, such as RCF2H interaction with chloride and water. It is noted that increased fluorination decreases the positive charge density on H but increases it on C, thus these interactions are dominated by electrostatic attraction to C over H.
Bruno A. Piscelli, Michael Bühl, Rodrigo A. Cormanich, David O'Hagan   +3 more
wiley   +2 more sources