Results 131 to 140 of about 431,045 (348)

Artificial Intelligence Revolution in Transcriptomics: From Single Cells to Spatial Atlases

Advanced Science, EarlyView.
Single‐cell RNA sequencing and spatial transcriptomics have unveiled cellular heterogeneity and tissue organization with unprecedented resolution. Artificial intelligence (AI) now plays a pivotal role in interpreting these complex data. This review systematically surveys AI applications across the entire analytic workflow and offers practical guidance ...
Shixin Li, Tianxiang Xiao, Yuanyuan Lan, Chengxiao Wu, Zhouying Li, Rong Liu, Qing Fang, Chao Zhang   +7 more
wiley   +1 more source

Quantitative Comparison of Ad‐Valorem Equivalents for Non‐Tariff Trade Measures: WTO Versus TRAINS

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Non‐tariff measures (NTMs) play a growing role in trade policy. Economists quantify NTMs by calculating their Ad Valorem Equivalents (AVE), typically employing one of two global NTM datasets: TRAINS from UNCTAD or WTO notifications. While TRAINS data better measure NTMs, their limited coverage over countries and time is inadequate for many ...
Sionegael Ikeme, Amanda M. Countryman, Dale T. Manning, Diane Charlton   +3 more
wiley   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai, Kosuke Matsui, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Hisashi Kosaka, Van Khanh Nguyen, Yasuhiro Ueno, Shuji Kariya, Masaki Kaibori   +9 more
wiley   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Essential Updates 2024/2025: History, Pathogenesis, Definition, Prevention, and Management of Small‐for‐Size Syndrome in Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami, Masashi Tsunematsu, Shinji Onda, Kenei Furukawa, Koichiro Haruki, Michinori Matsumoto, Yoshihiro Shirai   +6 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

First Successful Regeneration of a Structurally Native‐Like Colon Using a Bioabsorbable Polymer Sheet

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrated that a bioabsorbable polymer sheet (BAPS) can regenerate approximately half the circumference of the colon with native‐like structure and function in an experimental setting. As the model involved immediate closure after perforation and did not reproduce peritonitis, caution is required when considering clinical applicability ...
Junpei Takashima, Mitsuo Miyazawa, Masayasu Aikawa, Daisuke Fujimoto, Hirotoshi Kobayashi   +4 more
wiley   +1 more source

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

Applying Intraoperative Portal Venography in Liver Transplantation Vascular Surgery

Diagnostics
Background/Aim: Adequate portal inflow is essential for liver graft regeneration following transplantation. Intraoperative portal venography (IOPV) provides real-time assessment of portal vein patency, stenosis, thrombus formation, and portosystemic ...
Szu-Kai Wang, Yu-Fan Cheng, Wei-Xiong Lim, Chao-Long Chen, Leung-Chit Tsang, Chun-Yen Yu, Hsien-Wen Hsu, Po-Hsun Huang, Chun-Hua Chiu, Hsin-You Ou   +9 more
doaj   +1 more source

Refractory Hepatic Hydrothorax: A Rare Complication of Systemic Sclerosis and Presinusoidal Portal Hypertension

Case Reports in Hepatology, 2018
We report on a rare case of refractory hepatic hydrothorax in an individual with Scleroderma/CREST syndrome and noncirrhotic portal hypertension. Portal pressure measurements revealed a normal transjugular hepatic venous portal pressure gradient, mild ...
Gary A. Abrams, Robert Chapman, Samuel R. W. Horton   +2 more
doaj   +1 more source