Results 11 to 20 of about 340,481 (262)
Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]
, 2010 Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga +6 more
core +1 more source
Zaporožskij Medicinskij Žurnal, 2018 The morbidity of chronic pancreatitis (CP) remains at a high level. Over the past thirty years, more than doubled growth in the number of patients with chronic pancreatitis has been noted.
V. I. Pylypchuk
doaj +1 more source
Acta Medica Indonesiana, 2022 Background: Liver cirrhosis causes over one million deaths annually worldwide, but its prognosis varies depending on the presence of complications and decompensating events.
Raksheeth Agarwal, Wismandari Wisnu
doaj +2 more sources
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. [PDF]
, 2005 BACKGROUND: Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.
Bosch, J +12 more
core +1 more source
Portal Hypertensive Gastropathy: the Twilight Zone [PDF]
, 2014 As one of the major complication of liver cirrhosis, portal hypertensive gastropathy (PHG) should be an interesting topic to study. Until now the exact mechanism on how this phenomenon happened is yet, not clear.1 The occurrence of PHG is quite high in ...
Gani, R. A. (Rino)
core +1 more source
Terutroban, A TP-receptor antagonist, reduces portal pressure in cirrhotic rats [PDF]
, 2013 Increased production of vasoconstrictive prostanoids, such as thromboxane A2 (TXA2 ), contributes to endothelial dysfunction and increased hepatic vascular tone in cirrhosis.
Bosch i Genover, Jaume +6 more
core +2 more sources
Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension [PDF]
, 2016 BACKGROUND AND AIMS: Hepatic stellate cells (HSCs) are vital to hepatocellular function and the liver response to injury. They share a phenotypic homology with astrocytes that are central in the pathogenesis of hepatic encephalopathy, a condition in ...
Andreola, F +8 more
core +1 more source
Hepatic venous pressure gradient: clinical use in chronic liver disease [PDF]
Clinical and Molecular Hepatology, 2014 Portal hypertension is a severe consequence of chronic liver diseases and is responsible for the main clinical complications of liver cirrhosis. Hepatic venous pressure gradient (HVPG) measurement is the best available method to evaluate the presence and
Ki Tae Suk
doaj +1 more source
Portal Venous Pressure Variation during Hepatectomy: A Prospective Study
Acta Médica Portuguesa, 2019 Introduction: Excessive portal venous pressure in the liver remnant is an independent factor in the occurrence of posthepatectomy liver failure and small-for-size syndrome. The baseline portal pressure prior to hepatectomy was not considered previously.
Jorge Gomes Carrapita +8 more
doaj +1 more source
Pharmaceutics, 2020 Background: Portal hypertension is characterized by exaggerated activation of the renin-angiotensin-aldosterone axis. Natriuretic peptide system plays a counter-regulatory role, which is modulated by neprilysin.
Shao-Jung Hsu +6 more
doaj +1 more source