Results 21 to 30 of about 451,742 (343)
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure. [PDF]
PLoS ONE, 2013 OBJECTIVE: Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol.
Mercedes Reboredo +13 more
doaj +1 more source
Managing liver cirrhotic complications: Overview of esophageal and gastric varices [PDF]
Clinical and Molecular Hepatology, 2020 Managing liver cirrhosis in clinical practice is still a challenging problem as its progression is associated with serious complications, such as variceal bleeding that may increase mortality.
Cosmas Rinaldi Adithya Lesmana +2 more
doaj +1 more source
Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]
, 2010 Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga +6 more
core +1 more source
Zaporožskij Medicinskij Žurnal, 2018 The morbidity of chronic pancreatitis (CP) remains at a high level. Over the past thirty years, more than doubled growth in the number of patients with chronic pancreatitis has been noted.
V. I. Pylypchuk
doaj +1 more source
Acta Medica Indonesiana, 2022 Background: Liver cirrhosis causes over one million deaths annually worldwide, but its prognosis varies depending on the presence of complications and decompensating events.
Raksheeth Agarwal, Wismandari Wisnu
doaj +2 more sources
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. [PDF]
, 2005 BACKGROUND: Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.
Bosch, J +12 more
core +1 more source
Portal Hypertensive Gastropathy: the Twilight Zone [PDF]
, 2014 As one of the major complication of liver cirrhosis, portal hypertensive gastropathy (PHG) should be an interesting topic to study. Until now the exact mechanism on how this phenomenon happened is yet, not clear.1 The occurrence of PHG is quite high in ...
Gani, R. A. (Rino)
core +1 more source
EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study. [PDF]
VideoGIE, 2018 Background and aimsPortal hypertension is a serious adverse event of liver cirrhosis. Recently, we developed a simple novel technique for EUS-guided portal pressure gradient (PPG) measurement (PPGM).
Samarasena JB +7 more
europepmc +3 more sources
Terutroban, A TP-receptor antagonist, reduces portal pressure in cirrhotic rats [PDF]
, 2013 Increased production of vasoconstrictive prostanoids, such as thromboxane A2 (TXA2 ), contributes to endothelial dysfunction and increased hepatic vascular tone in cirrhosis.
Bosch i Genover, Jaume +6 more
core +2 more sources
Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension [PDF]
, 2016 BACKGROUND AND AIMS: Hepatic stellate cells (HSCs) are vital to hepatocellular function and the liver response to injury. They share a phenotypic homology with astrocytes that are central in the pathogenesis of hepatic encephalopathy, a condition in ...
Andreola, F +8 more
core +1 more source