Results 71 to 80 of about 451,742 (343)

Studies of the effects and modes of action of autonomic drugs on portal hemodynamics [PDF]

open access: yes, 1962
The effect of epinephrine, pitressin, and Arfonad on portal pressure has been studied in dogs with special emphasis on the role of the liver in determining pressure changes.
Butz, GW   +3 more
core  

Heart Failure Monitoring System Based on Wearable and Information Technologies [PDF]

open access: yes, 2007
In Europe, Cardiovascular Diseases (CVD) are the leading source of death, causing 45% of all deceases. Besides, Heart Failure, the paradigm of CVD, mainly affects people older than 65.
Arredondo Waldmeyer, Maria Teresa   +4 more
core   +2 more sources

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen   +3 more
wiley   +1 more source

Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements

open access: yesPortal Hypertension & Cirrhosis
Portal hypertension, the most common complication in liver cirrhosis, is characterized by a pathologic increase in portal venous pressure. Portal hypertension is defined as a pressure gradient greater than 5 mmHg between the portal vein and the inferior ...
Kathleen Möller   +7 more
doaj   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

open access: yesAdvanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge   +21 more
wiley   +1 more source

Palliative Portal Vein Stent Placement in Malignant and Symptomatic Extrinsic Portal Vein Stenosis or Occlusion [PDF]

open access: yes, 2018
This article evaluates the results of portal vein (PV) stent placement in patients with malignant extrinsic lesions stenosing or obstructing the PV and causing symptomatic PV hypertension (PVHT).
Bize, Pierre   +7 more
core  

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

open access: yesAdvanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang   +12 more
wiley   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu   +23 more
wiley   +1 more source

Etiology and Clinical Outcome of Budd-Chiari Syndrome and Portal Vein Thrombosis [PDF]

open access: yes, 2010
The liver receives approximately one-third of the resting cardiac output. Blood flow to the liver is supplied by both an arterial (hepatic artery) and a venous (portal vein) system and three hepatic veins provide drainage of blood from the liver to the ...
Hoekstra, J. (Jildou)
core   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

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