Results 51 to 60 of about 738,687 (307)

Modelling the antecedents of students’ satisfaction and continuous use intentions of an electronic appraisal portal system in higher education

open access: yesComputers in Human Behavior Reports
Developing and implementing appraisal portal systems for students can be highly beneficial for evaluating tutors’ teaching performances and providing constructive feedback to university authorities, thereby enhancing students’ learning experiences and ...
Brandford Bervell   +2 more
doaj   +1 more source

Unilateral Giant Varicocele Mimicking Inguinal Hernia Resulting from Portosystemic Shunt without Evidence of Portal Hypertension: An Unusual Case Report

open access: yesCase Reports in Surgery, 2013
Isolated giant varicocele has been reported with portal hypertension that results in abnormal communication between portal venous system and testicular vein venous system resulting in retrograde backflow of blood into the testicular venous system which ...
Muhammed Zahir   +3 more
doaj   +1 more source

Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation [PDF]

open access: yes, 2000
We tested the hypothesis that excessive portal venous supply of long-chain fatty acids to the liver contributes to the development of insulin resistance via activation of the hypothalamus-pituitary-adrenal axis (HPA axis) and sympathetic system.
Scheurink, AJW   +16 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Design Of Santri Admission Portal Admission Portal With E-Santri System

open access: yesCoreID Journal
The development and implementation of the e-Santri portal system for new student admissions at As-Syafi’iah Islamic Boarding School has significantly improved the efficiency and accuracy of the registration process.
Rd. Imam Saepul Millah
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Testing Ecology: Breast and Gynecological Cancer Predisposition Tests and the National Healthcare System in Spain [PDF]

open access: yes
[EN] This research asks what is being put to the test by breast and gynecological cancer predisposition testing in Spain beyond genes or cancer. By combining document analysis and fieldwork with national healthcare professionals and drawing on the ...
Argudo-Portal, Violeta   +1 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Legislative update [PDF]

open access: yes, 2017
Newsletter of the Teacher Retirement System of Texas providing updated information about programs, benefits, and related ...
Teacher Retirement System of Texas
core  

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