Results 151 to 160 of about 63,636 (348)

Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta‐Analysis of Outcomes

open access: yesArtificial Organs, EarlyView.
Dialysis‐enhanced EVMP effectively maintains biochemical homeostasis, potentially mitigating metabolic stress and extending perfusion duration. Functional outcomes varied depending on the organ type, with the most pronounced benefits observed in cardiac perfusion.
Yomna E. Dean   +12 more
wiley   +1 more source

Biliary Glutathione as a Potential Marker for Viability Assessment of Cholangiocytes During Normothermic Machine Perfusion of Livers

open access: yesArtificial Organs, EarlyView.
This study identifies biliary glutathione concentration during normothermic machine perfusion as a potential biomarker for biliary viability. Increasing GSH levels correlate with fewer biliary complications post‐transplant, supporting its role in assessing graft quality and improving decision‐making in liver transplantation.
Christina Bogensperger   +10 more
wiley   +1 more source

Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Extracellular matrix (ECM) remodelling biomarkers reflect portal hypertension and disease severity in advanced chronic liver disease (ACLD). However, their predictive value for disease progression is largely restricted to compensated ACLD (cACLD). ABSTRACT Background Extracellular matrix (ECM) remodelling in advanced chronic liver disease (ACLD) is ...
Benedikt Simbrunner   +17 more
wiley   +1 more source

Indocyanine Green Clearance Correlates With Biomarkers Reflecting Key Disease‐Driving Mechanisms in Advanced Chronic Liver Disease and Predicts Acute‐on‐Chronic Liver Failure and Death

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs   +17 more
wiley   +1 more source

Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Diabetes mellitus independently increases the risk of hepatic encephalopathy following TIPS placement in patients with cirrhosis. These findings emphasize the need for careful risk assessment in patients with cirrhosis and portal hypertension complications undergoing TIPS.
Michelle Spaan   +16 more
wiley   +1 more source

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