Results 171 to 180 of about 156,942 (381)
Hepatic encephalopathy (HE) is a frequent complication that arises subsequent to transjugular intrahepatic portosystemic shunt (TIPS) procedures, with a considerable impact on patient prognosis. The occurrence of HE is influenced by multiple factors, and various risk prediction models have been developed in recent years to forecast its development post‐
Lixin Song, Xinyi Qiao, Yu Sun, Hui Yang
wiley +1 more source
Obesity, MASH and Statins: Insights from a PBPK/PD Zonal Liver Model. ABSTRACT Statins are frequently prescribed for hyperlipidemia, a common comorbidity in patients with obesity and/or metabolic dysfunction‐associated steatohepatitis (MASH). However, limited knowledge exists on how MASH may alter statin disposition within hepatocytes where the statin ...
William A. Murphy +5 more
wiley +1 more source
Population Pharmacokinetics of Asundexian in People at Risk for Thromboembolic/Cardiovascular Events
ABSTRACT Asundexian is a potent, selective, and reversible inhibitor of activated clotting Factor XI currently under development for secondary prevention of recurrent ischemic stroke in the ongoing Phase III OCEANIC‐STROKE study (NCT05686070). Here, we report the development of a population pharmacokinetic (popPK) model for asundexian.
Ashraf Yassen +7 more
wiley +1 more source
ABSTRACT This paper examines the nexus between financial markets (FM), mineral resources, and global energy transitions (ET) between 1990 and 2023 in the 20 leading countries exporting mineral resources, focusing on their impact on environmental sustainability.
Hamza Akram +5 more
wiley +1 more source
Venous-right atrial bypass for superior vena cava thrombosis during orthotopic liver transplantation [PDF]
Antonio D. Pinna +14 more
core +1 more source
eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha +6 more
wiley +1 more source

