Results 171 to 180 of about 156,942 (381)

Advances in Factors and Risk Prediction of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Hepatic encephalopathy (HE) is a frequent complication that arises subsequent to transjugular intrahepatic portosystemic shunt (TIPS) procedures, with a considerable impact on patient prognosis. The occurrence of HE is influenced by multiple factors, and various risk prediction models have been developed in recent years to forecast its development post‐
Lixin Song, Xinyi Qiao, Yu Sun, Hui Yang
wiley   +1 more source

Impact of Obesity and MASH on Zonal Hepatocellular Statin Exposure: Pharmacodynamic Insights From a Permeability‐Limited Multicompartment Liver Model

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Obesity, MASH and Statins: Insights from a PBPK/PD Zonal Liver Model. ABSTRACT Statins are frequently prescribed for hyperlipidemia, a common comorbidity in patients with obesity and/or metabolic dysfunction‐associated steatohepatitis (MASH). However, limited knowledge exists on how MASH may alter statin disposition within hepatocytes where the statin ...
William A. Murphy   +5 more
wiley   +1 more source

Population Pharmacokinetics of Asundexian in People at Risk for Thromboembolic/Cardiovascular Events

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Asundexian is a potent, selective, and reversible inhibitor of activated clotting Factor XI currently under development for secondary prevention of recurrent ischemic stroke in the ongoing Phase III OCEANIC‐STROKE study (NCT05686070). Here, we report the development of a population pharmacokinetic (popPK) model for asundexian.
Ashraf Yassen   +7 more
wiley   +1 more source

A case report of portal-systemic encephalopathy with normal portal venous pressure and no cirrhosis of the liver in a hemodialysis patient.

open access: bronze, 1996
Tomoichiro Onishi   +5 more
openalex   +2 more sources

Elevated Liver Regeneration in Response to Pharmacological Reduction of Elevated Portal Venous Pressure by Terlipressin After Partial Hepatectomy

open access: yesTransplantation, 2014
R. Fahrner   +7 more
semanticscholar   +1 more source

Interlinkages Between Financial Markets and Minerals (1990–2023): Implications for Global Energy Transitions and Environmental Sustainability

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper examines the nexus between financial markets (FM), mineral resources, and global energy transitions (ET) between 1990 and 2023 in the 20 leading countries exporting mineral resources, focusing on their impact on environmental sustainability.
Hamza Akram   +5 more
wiley   +1 more source

Venous-right atrial bypass for superior vena cava thrombosis during orthotopic liver transplantation [PDF]

open access: yes, 1997
Antonio D. Pinna   +14 more
core   +1 more source

eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation

open access: yesSmall, EarlyView.
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy