Results 61 to 70 of about 57,438 (322)

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

open access: yes, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris   +17 more
core   +1 more source

The Portal Venous Pressure in Man

open access: yesExperimental Biology and Medicine, 1942
Mall1, 2 appears to have been the first to record the portal venous pressure in animals under experimental conditions. The later determinations by Burton-Opitz3, 4, 5 were shortly followed by Tiger-stedt's6 records. These observers used the technically difficult T-cannulation of the portal vein, although this itself probably interfered with the normal ...
openaire   +2 more sources

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

open access: yesAdvanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen   +24 more
wiley   +1 more source

Endoscopic Ultrasound-Guided Portal Pressure Measurement and Interventions [PDF]

open access: yesClinical Endoscopy, 2018
A growing number of studies have explored endoscopic ultrasound (EUS)-guided vascular catheterization. Potential clinical applications of EUS-guided portal venous access include angiography, measurement of the portosystemic pressure gradient, EUS-guided ...
Jason B. Samarasena, Kenneth J. Chang
doaj   +1 more source

Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]

open access: yes, 2018
It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P   +5 more
core   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

open access: yesAdvanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen   +8 more
wiley   +1 more source

Major hepatic resection and portal pressure [PDF]

open access: yes, 1977
Although other reports have stressed the inevitability of portal hypertension and splanchnic pooling following major liver resections, clinical observations during 30 major hepatic resections and measurements of portal pressure in three consecutive ...
Buerk, CA, Putnam, CW, Starzl, TE
core  

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

open access: yesAdvanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng   +9 more
wiley   +1 more source

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis.

open access: yesPLoS ONE, 2019
BACKGROUND:Prostanoids are important regulators of platelet aggregation and thrombotic arterial diseases. Their involvement in the development of portal vein thrombosis, frequent in decompensated liver cirrhosis, is still not investigated.
Alexander Queck   +15 more
doaj   +1 more source

Two‐Stage Treatment for Adult Large Patent Ductus Venosus

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This is the first report of a two‐stage treatment for an adult large PDV involving the first stage surgical angioplasty of the large Arantius' duct and second stage embolization of the formed small Arantius' duct. The two‐stage approach could avoid embolic material migration into the systemic circulation or acute portal hypertension associated with the
Shohei Kudo   +4 more
wiley   +1 more source

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