Results 81 to 90 of about 156,942 (381)

EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study. [PDF]

open access: yes, 2018
Background and aimsPortal hypertension is a serious adverse event of liver cirrhosis. Recently, we developed a simple novel technique for EUS-guided portal pressure gradient (PPG) measurement (PPGM).
Chang, Kenneth J   +7 more
core  

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

open access: yes, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris   +17 more
core   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu   +23 more
wiley   +1 more source

National Consensus on Portal Hypertension Management in Indonesia

open access: yesActa Medica Indonesiana, 2022
Portal hypertension is a clinical syndrome that consists of hypersplenism, ascites, gastroesophageal varices, and encephalopathy. This condition is marked by increased portal pressure gradient and may occur with or without liver cirrhosis.
Juferdy Kurniawan   +7 more
doaj   +2 more sources

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis.

open access: yesPLoS ONE, 2019
BACKGROUND:Prostanoids are important regulators of platelet aggregation and thrombotic arterial diseases. Their involvement in the development of portal vein thrombosis, frequent in decompensated liver cirrhosis, is still not investigated.
Alexander Queck   +15 more
doaj   +1 more source

Innovative application of an implantable venous access system in the portal vein: technique, results and complications in three dogs

open access: yesBMC Veterinary Research, 2019
Background Vascular access port (VAP) systems are widely used in human medicine to provide long-term venous access. However, in veterinary medicine the use of VAP systems is not common practice and publications on their potential applications have been ...
Kiona S. de Nies   +7 more
doaj   +1 more source

A Dynamic DNA Nano‐Antioxidant Targeting Galectin‐3 Attenuates Liver Fibrosis via Reducing Macrophage Oxidative Stress

open access: yesAdvanced Science, EarlyView.
This study developed a dynamic DNA nano‐antioxidant (DDN) for Galectin‐3 siRNA delivery, specifically targeting hepatic macrophages to suppress ROS‐driven fibrosis. DDN enhanced hepatic accumulation, restored NRF2 signaling, and attenuated oxidative stress, collagen deposition, and fibrotic progression in a CCl4‐induced cirrhosis model, demonstrating ...
Mengjia Peng   +6 more
wiley   +1 more source

Effect of Pulse Shaping on Subharmonic Aided Pressure Estimation In Vitro and In Vivo. [PDF]

open access: yes, 2016
OBJECTIVES: Subharmonic imaging (SHI) is a technique that uses the nonlinear oscillations of microbubbles when exposed to ultrasound at high pressures transmitting at the fundamental frequency ie, f METHODS: Eight waveforms with different envelopes were ...
Dave, Jaydev K.   +11 more
core   +2 more sources

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu   +13 more
wiley   +1 more source

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

open access: yes, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia   +5 more
core   +1 more source

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