Analysis of the growth trajectories of junior residents in Japan: a longitudinal cohort study using data from a nationwide e-portfolio system (EPOC2). [PDF]
Nawa N+11 more
europepmc +1 more source
APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus
Molecular dynamics simulations and in silico screening were used to identify non‐competitive inhibitors of APH, the enzymes that confer resistance to aminoglycoside antibiotics. A hit molecule showed activity against APH(2′′)‐IVa. Allosteric inhibition by the hit molecule and a two‐fold more potent analogue was confirmed by enzymatic measurements. Both
Elise Kaplan+6 more
wiley +1 more source
A qualitative study exploring the experiences of advanced clinical practitioner training in emergency care in the South West of England, United Kingdom. [PDF]
Ablard S+5 more
europepmc +1 more source
Asset Pricing and Optimal Portfolio Choice in the Presence of Illiquid Durable Consumption Goods
Sanford J. Grossman, Guy Laroque
openalex +1 more source
An adapted Black Widow Optimization Algorithm for Financial Portfolio Optimization Problem with cardinalty and budget constraints. [PDF]
Khodier R, Radi A, Ayman B, Gheith M.
europepmc +1 more source
A note on Merton's “Optimum Consumption and Portfolio Rules in a continuous-Time Model”
Suresh Sethi, Michael Taksar
openalex +1 more source
Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe+4 more
wiley +1 more source
Emissions Disclosures and Energy Use Reporting by Hospitals in the United States. [PDF]
Abel A+6 more
europepmc +1 more source
Labor Supply Flexibility and Portfolio Choice
Zvi Bodie, William Samuelson
openalex +1 more source
ABSTRACT The climate transition is increasingly acknowledged as a major risk driver for companies, financial institutions, and investors. At the same time, there is widespread confusion about how to best measure climate transition risk, since different measurements lead to significantly different risk profiles. I show empirically that, to date, the two
Philip Fliegel
wiley +1 more source