Results 31 to 40 of about 333,468 (215)

AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design

open access: yesmAbs, 2020
As biologics have become a mainstay in the development of novel therapies, protein engineering tools to expand on their structural advantages, namely specificity, affinity, and valency are of interest.
Mario Sanches   +13 more
doaj   +1 more source

Methodological tensions for non-Indigenous people in Indigenous research: A critique of critical discourse analysis in the Australian context

open access: yesSocial Sciences and Humanities Open, 2022
There are complex ethical issues about appropriate roles, responsibilities and methodologies for non-Indigenous people researching Indigenous Peoples and contexts. As a research methodology, critical discourse analysis (CDA) may expose colonial power and
Julia McCartan   +2 more
doaj   +1 more source

Identification of N-acylethanolamines in Dictyostelium discoideum and confirmation of their hydrolysis by fatty acid amide hydrolase[S]

open access: yesJournal of Lipid Research, 2013
N-acylethanolamines (NAEs) are endogenous lipid-based signaling molecules best known for their role in the endocannabinoid system in mammals, but they are also known to play roles in signaling pathways in plants.
Alexander C. Hayes   +3 more
doaj   +1 more source

Country Portfolios [PDF]

open access: yesSSRN Electronic Journal, 2000
Capital flows to developing countries are small and are mostly take the form of loans rather than direct foreign investment. We build a simple model of North-South capital flows that highlights the interplay between diminishing returns, production risk and sovereign risk.
Kraay, Aart   +3 more
openaire   +5 more sources

Portfolio and prosper [PDF]

open access: yesNature Human Behaviour, 2019
PhD students produce more than publications; they create a wealth of resources as a means to their research. Matt Crump, Associate Professor at the City University of New York, argues that PhDs should share these resources as portfolios that demonstrate their skills and to benefit the scientific community.
openaire   +2 more sources

The impact of non-pharmaceutical interventions on SARS-CoV-2 transmission across 130 countries and territories

open access: yesBMC Medicine, 2021
Background Non-pharmaceutical interventions (NPIs) are used to reduce transmission of SARS coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19). However, empirical evidence of the effectiveness of specific NPIs has been inconsistent.
Yang Liu   +5 more
doaj   +1 more source

Municipal Compost as a Nutrient Source for Organic Crop Production in New Zealand

open access: yesAgronomy, 2016
About 1% of New Zealand farmland is managed organically. Nitrogen is the nutrient most likely to limit organic crop production. A potential solution is incorporation of compost to supply N.
Abie Horrocks   +3 more
doaj   +1 more source

Portfolio Optimization [PDF]

open access: yesASTIN Bulletin, 2000
AbstractBased on the profit and loss account of an insurance company we derive a probabilistic model for the financial result of the company, thereby both assets and liabilities are marked to market. We thus focus on the economic value of the company.We first analyse the underwriting risk of the company. The maximization of the risk return ratio of the
openaire   +1 more source

Ensuring successful implementation of portfolios in medical institutions: Potential challenges and solutions

open access: yesJournal of the Scientific Society, 2021
The portfolio refers to a collection of documents supporting learning over a period of time and essentially includes reflection on learning. The present review was carried out to explore the practices required for the successful implementation of ...
Saurabh RamBihariLal Shrivastava   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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