Results 31 to 40 of about 89,301 (246)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Towards Predictive Maintenance in the Maritime Industry: A Component-Based Overview

open access: yesJournal of Marine Science and Engineering
The maritime industry has a significant influence on the global economy, underscoring the need for operational availability and safety through effective maintenance practices.
Alexandros S. Kalafatelis   +5 more
doaj   +1 more source

Analysis of the economic impact of the downspout of the river in the ports of Paraguay, 2019−2020

open access: yesPoblación y Desarrollo, 2022
The research aims to analyze the economic impact of the downspout of the river in the ports of Paraguay, 2019-2020. It was based on a quantitative, non-experimental, cross-sectional and descriptive design approach. 42 participants (twelve shipping agency
Ana María del Rosario Franco Medina   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

Improving Connectivity in 6G Maritime Communication Networks With UAV Swarms

open access: yesIEEE Access
The deployment of maritime communication networks (MCNs) enables Internet-of-Things (IoT) applications, related to autonomous navigation, offshore facilities and smart ports.
Nikolaos Nomikos   +5 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

HOODIE: Hybrid Computation Offloading via Distributed Deep Reinforcement Learning in Delay-Aware Cloud-Edge Continuum

open access: yesIEEE Open Journal of the Communications Society
Cloud-Edge Computing Continuum (CEC) system, where edge and cloud nodes are seamlessly connected, is dedicated to handle substantial computational loads offloaded by end-users.
Anastasios E. Giannopoulos   +3 more
doaj   +1 more source

Déconstruire la cartographie des relations sino-africaines : le cas des ports

open access: yesRevue Internationale des Études du Développement, 2023
This article offers a critical view of university cartographic productions regarding the roles of the Chinese in African ports. For this purpose, a cartographic counter-representation of these forms of Chinese presence is generated in order first to take
Xavier Aurégan
doaj   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat   +5 more
wiley   +1 more source

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