Results 71 to 80 of about 1,182,692 (300)

Position Statement, January 31, 1977 [PDF]

open access: yes, 1977
Position Statement report produced by Iowa Social Services Department to show progress in this ...

core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

International Federation of Endodontic Associations education committee position statement on the management of internal root resorption: Suggested clinical protocol

open access: yesEndodontology
Internal root resorption (IRR) results due to loss or damage of the predentin layer around the pulp chamber/root canal in association with a chronic inflammatory process. Multiple variables, such as traumatic injury, orthodontic tooth movement, excessive
Özgür Ilke Atasoy Ulusoy   +4 more
doaj   +1 more source

MVC-Based Modeling Support for Embedded Real-Time Systems

open access: yes, 1999
Introduction Several software architecture paradigms have been proposed for the development of interactive software systems and applications. Their common idea is the separation of user interface components from application logic.
Position Statement Stefan
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Position statement: Giftedness in the early years

open access: yes, 2015
This position paper has been developed by giftEDnz, the professional association for gifted education to promote evidence-based practice in the early years in supporting gifted and talented children in the early years (age birth - 8 years old)
White VK, Delaune A, Dean J
core  

Smoking, vaping and heart health position statement

open access: yes
This position statement outlines key findings and recommendations from the Heart Foundation on the relationship between, smoking and heart disease, and vaping and heart disease, in New Zealand adults.
Heart Foundation
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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