Advanced Science, EarlyView.A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo +10 more
wiley +1 more source
, 2001 Decision Feedback Equaliation (DFE) aided wideband Burst-by-Burst (BbB) Adaptive Trellis Coded Modulation (TCM), Turbo Trellis Coded Modulation (TTCM) and Bit-Interleaved Coded Modulation (BICM) are proposed and characterised in performance terms over ...
Ng, S.X., Cherriman, P.J., Hanzo, L.
core
Reconsidering Intraoperative Hip Positioning in Single-Position Lateral Lumbar Interbody Fusion - A Commentary on "Optimal Positioning for Single-Position Lateral Lumbar Interbody Fusion". [PDF]
NeurospineChen J.
europepmc +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
Advanced Science, EarlyView.ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
TriQuery-BEV: Enhancing 3D Perception for Autonomous Driving with Temporal Query Filtering and Uncertainty-Aware Fusion. [PDF]
Sensors (Basel)Dong J, Chen X, Liu Z.
europepmc +1 more source
Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
Visual and Positional Modulation of Pendular Seesaw Nystagmus: Implications for the Mechanism
, 2019 Background: The mechanisms of pendular seesaw nystagmus (SSN) remain unknown. Methods: We evaluated modulation of pendular SSN by removal of visual fixation, convergence, and positional changes in 2 patients, one with bitemporal hemianopia due to a ...
Sung-Hee Kim; Hyo-Jung Kim; Sea-Won Oh; Ji-Soo Kim
core
Clinical Heterogeneity in Vestibular Migraine Diagnosed Using Bárány Society Criteria: Differences According to Caloric-Test-Based Evidence of Peripheral Vestibular Dysfunction. [PDF]
J Clin NeurolWang Y +8 more
europepmc +1 more source
Advanced Science, EarlyView.A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang +7 more
wiley +1 more source
Word frequency modulates the use of initial and final morpheme positional probabilities during Chinese sentence reading in L2 learners: an eye-tracking study. [PDF]
Front PsycholSong T, Zhang T.
europepmc +1 more source