Results 21 to 30 of about 718,685 (289)

PCSK9 as a Positive Modulator of Platelet Activation

Journal of the American College of Cardiology, 2018
High circulating levels of proprotein convertase subtilisin/kexin 9 (PCSK9) were shown to be predictive of cardiovascular events in patients with atrial fibrillation and in those with acute coronary syndrome [(1,2)][1]. Because high PCSK9 plasma levels were significantly correlated with 11-dehydro-
Camera, Marina, Rossetti, Laura, Barbieri, Silvia S., Zanotti, Ilaria, Canciani, Barbara, Trabattoni, Daniela, Ruscica, Massimiliano, Tremoli, Elena, Ferri, Nicola   +8 more
openaire   +3 more sources

Benign Paroxysmal Positional Vertigo: Is It Really an Otolith Disease?

, 2022
The current theory in physiopathology of benign paroxysmal positional vertigo is the mechanical theory, namely the cupulolithiasis-canalolithiasis theory. Repositioning maneuvers based on this theory has now taken place in therapy.
Koc, Ahmet, Ahmet Koç
core   +1 more source

Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes

Stem Cell Reports, 2017
Summary: Modulation of transcription, either synthetic activation or repression, via dCas9-fusion proteins is a relatively new methodology with the potential to facilitate high-throughput up- or downregulation studies of gene function. Genetic studies of
Seok-Man Ho, Brigham J. Hartley, Erin Flaherty, Prashanth Rajarajan, Rawan Abdelaal, Ifeanyi Obiorah, Natalie Barretto, Hamza Muhammad, Hemali P. Phatnani, Schahram Akbarian, Kristen J. Brennand   +10 more
doaj   +1 more source

Prevalence of positional nystagmus during static positional testing in normal healthy population using video-nystagmography

, 2010
Positional nystagmus (PN) is a type of nystagmus that occurs as a result of the head or the head and body being moved from one position to another and then statically maintained in the critical position.
Svandelkova, Irena
core   +2 more sources

Experimental coder/decoder of dicode pulse position modulation. [PDF]

, 2009
Dicode Pulse Position Modulation has been proposed as an alternative coding scheme which has many advantages over previous Pulse Position Modulation formats.
Charitopoulos, Romanos, Sibley, Martin J.N.   +1 more
core   +4 more sources

PSD and light source modulation based cooperative target pose detection method

四川大学学报. 自然科学版, 2022
The relative position and attitude detection of space targets is the focus of research in the field of spacecraft docking, and the detection methods are mainly divided into two categories: telemetry and optical measurement methods. Among them, the latter
CHENG Shao-Wei, LIU Jin, ZHANG Peng-Cheng, YANG Hai-Ma, ZHAO Hong-Zhuang, YUAN Xue-Qi   +5 more
doaj  

Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum

Frontiers in Genetics, 2012
TThe corpus callosum is the main commissure connecting left and right cerebral hemispheres, and varies widely in size. Differences in the midsagittal area of the corpus callosum (MSACC) have been associated with a number of cognitive and behavioral ...
Alex J Newbury, Glenn D Rosen
doaj   +1 more source

Control and controllability of microswimmers by a shearing flow

Royal Society Open Science, 2021
With the continuing rapid development of artificial microrobots and active particles, questions of microswimmer guidance and control are becoming ever more relevant and prevalent. In both the applications and theoretical study of such microscale swimmers,
Clément Moreau, Kenta Ishimoto, Eamonn A. Gaffney, Benjamin J. Walker   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells

Scientific Reports, 2023
Alterations in centrosome proteins may result in centrosome abnormalities such as disorganized spindles and centrosome amplification, leading to aneuploidy and genomic instability.
Laxmidhar Das
doaj   +1 more source