Results 221 to 230 of about 74,287 (305)

Automated Ultrasound‐Based Analysis of Urethral Kinematics in Stress Urinary Incontinence: A Pilot Study

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Stress urinary incontinence (SUI) has been linked to excessive urethral mobility, yet clinical evaluation has been largely limited to assessing maximal excursion rather than capturing the full dynamics of visible urethral movement. In this study, we hypothesize that an automated, ultrasound‐based method can objectively differentiate
Kourosh Kalayeh   +5 more
wiley   +1 more source

Clinician insights into pediatric temporary feeding tube management: Unseen barriers, unclear roles revealed from a prospective mixed methods study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Temporary feeding tubes are common in pediatric healthcare, but research on understanding how clinicians manage their use and understand the impact on families is limited. Existing research often overlooks clinician perspectives despite tensions between clinical priorities and family needs. This study aimed to understand clinicians'
Claire Reilly   +4 more
wiley   +1 more source

Enhancing patient positioning accuracy: evaluating daily cone beam computed tomography in the halcyon system. [PDF]

open access: yesJpn J Clin Oncol
Tai DT   +7 more
europepmc   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG‐CoA Reductase for Coronary Artery Disease Treatment

open access: yesChemistryOpen, EarlyView.
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo   +4 more
wiley   +1 more source

Engineering Dosimetric Excellence In Total Body Irradiation: Tomotherapy‐Driven Protocols for Precision and Reproducibility

open access: yesPrecision Radiation Oncology, EarlyView.
• Objective: Assess helical Tomotherapy‐based TBI for clinical feasibility, dosimetric reproducibility, and in‐vivo accuracy using dual‐orientation simulation and patient‐specific QA. • Methodology: Implementation of ArcCHECK 3D diode array, ionization chamber verification, and in‐vivo dosimetry with OSLDs at 16 anatomical sites to ensure precise dose ...
Sandeep Singh   +8 more
wiley   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

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