Results 181 to 190 of about 28,081 (286)

Beyond co-creation: why community-centered research ecosystems and advancing community research capacity building is implementation science's next frontier. [PDF]

Implement Sci Commun
Teh AHY, Chong SY, Ong EJ.
europepmc   +1 more source

3D Printed Meter‐Scale Soft Origami Robots Capable of Load‐Bearing Actuation Via Crease Stiffness Modulation

Advanced Science, EarlyView.
Origami has inspired numerous soft deployable mechanisms for safe human‐robot interaction, while its intrinsic kinematic instability at arbitrary configurations limited their practical robotic application. This work presents a 3D printed meter‐scale origami robotic actuator capable of load‐bearing deformation through creaseline stiffness modulation.
Sung Yol Yu, Sang‐Joon Ahn, Wonchul Lee, Seunguk Moon, Hyun‐Jin Hong, Kyu‐Jin Cho   +5 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Likelihood of Treatment Access and Barriers to Treatment by Substance Use Recovery Status Among United States Adults. [PDF]

Stigma Health
Schick MR, Planas-García B, Perez J, Kelly LM.   +3 more
europepmc   +1 more source

Ethnographic methods intoxication and research positionality

, 2015
Blackman, S.
core  

High‐Power Hybrid Nanogenerator With Multi‐Degree‐of‐Freedom Mechanical Coupling for Harvesting Water Wave Energy

Advanced Science, EarlyView.
A high‐power hybrid nanogenerator (HP‐HNG) with multi‐degree‐of‐freedom mechanical coupling is reported, integrating multi‐directional wave energy for output to achieve 1 + 1 > 2 energy harvesting. The HP‐HNG achieves a peak output power of 0.764 W, corresponding to a peak power density of 127.303 W m−3. At a wave frequency of 1 Hz, the HP‐HNG delivers
Shuai Ding, Hua Zhai, Hao Gong, Xiao Long, Yuanzhuo Tian, Zhanyong Hong, Long Zheng, Xucong Wang, Xiangyu Chen, Zhong Lin Wang   +9 more
wiley   +1 more source

Sport and recreation for Indigenous peoples with neurodevelopmental disabilities in Canada: an empty scoping review and call to action. [PDF]

Front Rehabil Sci
Bruno G, Andreasen S, Ahmad M, Littlechild T, Roy C, Cuzzolino B, Sokol E, Landon W, McMorris CA.   +8 more
europepmc   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Evidence-biased medicine? Applying a health equity lens to Sackett's methodological framework. [PDF]

Br J Gen Pract
Mitchell C, Hagan T, Fryer K, Reynolds J, Mawson R, Huang Q, Emery L, Duke B, Patel MG.   +8 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source