Results 31 to 40 of about 28,081 (286)

How positionality influences engineering design-for-social-good work: insights from practitioners and students

Design Science
Engineering design applications that emphasize positive societal impacts are growing in popularity, yet often overlook the critical importance of engineering designers’ and stakeholders’ positionalities – their unique identities, experiences and ...
Nick Moses, Shanna R. Daly, Deepansha Singh, Smriti Vamaraju, Ted London, Deepa Butoliya, Kathleen Helen Sienko   +6 more
doaj   +1 more source

To be or not to be – ‘insider/outsider positionality’: Methodological challenges in researching a group of Iraqi Kurdish migrants in the UK

, 2023
The relationship between the researcher(s), the research, and the research participants has been a recurrent concern in the methodology literature.
Mahmud, C.
core  

How Might Positionality Be Used in Biblical Studies? Philippians 1:27–2:4 as an Example

Religions
Using Philippians 1:27–2:4 as an example, this article will explore the role of positionality in biblical studies. Although the process of reflecting on one’s positionality is more prevalent in empirical-based research, one’s positionality is also ...
Melissa C. M. Tan
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Between a Rock and a Hard Place: Ethics of Fieldwork in Northwest Pakistan

International Quarterly for Asian Studies, 2023
In the wake of the US-led and Pakistan-allied “war on terror”, residents in Northwest Pakistan have faced inconceivable structural and physical violence, in ways that pose ethical challenges in ethnographic writing and research.
Ping-hsiu Alice Lin
doaj   +1 more source

Positionality: Reflecting on the Research Process [PDF]

, 2014
Through this article, the author provides a reflection on the role of positionality in research, following the completion of a qualitative research project.
Bourke, Brian
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Weaponised Positionality? Coercive Disclosure in the "Publish or Perish" Academy

Swiss Journal of Sociocultural Anthropology
This paper brings anthropological scholarship on reflexivity and positionality in conversation with debates around issues of self-exploitation in the neoliberal university, to argue that the publication pressures early career anthropologists face, can ...
Sandhya Fuchs
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Autohistoria: Traversing through Time and Space to Explore Identity, Consciousness, Positionality, and Power

Genealogy, 2020
How do our own cultural-historical experiences in geographic spaces like the border(s) we occupy shape our identities, consciousness, positionality, and power?
Belinda Bustos Flores
doaj   +1 more source