Results 41 to 50 of about 2,749,924 (279)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Electronic based accuracy enhancement of CNC machine tools [PDF]

The need for better machine tool accuracy is discussed together with the factors which can affect machine tool accuracy. A study is made of the various techniques adopted for the reduction of errors in machine tools. The concept of error compensation
Postlethwaite, Scott R.
core   +4 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A quadratic weighted centroid algorithm for tunnel personnel positioning

International Journal of Distributed Sensor Networks, 2020
To improve the accuracy and generalization of tunnel personnel positioning systems, this article proposes a quadratic weighted centroid algorithm. By adopting a Gaussian filter model to improve the range accuracy of the received signal strength indicator
Haiying Wang, Linhao Liang, Jian Xu, Hui She, Wuxiang Li   +4 more
doaj   +1 more source

The Influence of the Movement Method on the Results of Machine Tool Positioning Accuracy Analysis

Measurement Science Review, 2023
The improvement of machine tools, and therefore, of industrial production, requires high accuracy of machining while adapting to the different dimensions of the workpieces and to the machines themselves. As a result, the improvement of testing procedures
Budimir Alexander, Tabaković Slobodan, Zeljković Milan   +2 more
doaj   +1 more source

INVESTIGATION OF POSITION ACCURACY IN UAVS

Turkish Journal of Remote Sensing, 2023
Digital Terrain Models (DTMs) are used as basic data in many engineering projects. In addition to classical terrestrial techniques, space and satellite techniques and Unmanned Aerial Vehicles (UAVs) are coomonly used in the production of the DTMs. In the production of the DTM with the help of the UAVs, measurements can be made easily where people can ...
Ömer YILDIRIM, Cevat İNAL, Sercan BÜLBÜL, Burhaneddin BİLGEN   +3 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source