Results 191 to 200 of about 232,272 (307)

Holistic integrative analysis of circulatory parameters: effects of CPAP titration in patients with obstructive sleep apnea. [PDF]

J Thorac Dis
Chen JH, Sun XG, Xiang MJ, Zhang ZF, Huang J, Xie B, Xu F, Zhou QQ, Wang JN, Zhang YF, Shi C, Liu F, Xie YH.   +12 more
europepmc   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source

Home-based respiratory-gated transcutaneous auricular vagus nerve stimulation for rheumatoid arthritis-a feasibility study. [PDF]

Clin Rheumatol
Parikh A, Lewis G, GholamHosseini H, Ng KPL, Kluger M, Almesfer F, Chang WL, Rice D.   +7 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Photosynthetic Light Response Curve and Photosynthetic Performance of Cacao (<i>Theobroma cacao</i> L.) Genotypes Grown Under Full Sun Field Conditions. [PDF]

Plants (Basel)
de Santana EN, Kuhlcamp KT, Crasque J, Cerri Neto B, Oliveira VS, Dousseau-Arantes S.   +5 more
europepmc   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

From kidney injury to cardiac dysfunction: the central role of oxidative stress in diabetes and CKD. [PDF]

Basic Res Cardiol
Sen P, Sittig T, Hamers J, d'Ambrosio L, Ornek I, Zhang J, Shashikadze B, Stöckl JB, Bachter M, Bierschenk S, Renner S, Wolf E, Clauss S, Fröhlich T, Nickel AG, Maack C, Merkus D.   +16 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Positive Airway Pressure Therapies for Heart Failure: What Do the Trials Tell Us? [PDF]

Card Fail Rev
Pec J, Arzt M.
europepmc   +1 more source

The Design and Application of Positive Pressure Respirators [PDF]

Postgraduate Medical Journal, 1961
openaire   +2 more sources