Results 21 to 30 of about 97,911 (216)

Safety in intrahospital transportation: evaluation of respiratory and hemodynamic parameters. A prospective cohort study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Intrahospital transportation of mechanically ventilated patients is a high-risk situation. We aimed to determine whether transfers could be safely performed by using a transportation routine.
Bruno Franco Mazza, José Luiz Gomes do Amaral, Heloisa Rosseti, Rosana Borges Carvalho, Ana Paula Resque Senna, Hélio Penna Guimarães, Flavia Ribeiro Machado   +6 more
doaj   +1 more source

Effect of Positive End-Expiratory Pressure on Central Venous Pressure in Patients under Mechanical Ventilation

Archives of Academic Emergency Medicine, 2018
Introduction: Finding the probable governing pattern of PEEP and CVP changes is an area of interest for in-charge physicians and researchers. Therefore, the present study was designed with the aim of evaluating the relationship between the mentioned ...
Majid Shojaee, Anita Sabzghabaei, Hossein Alimohammadi, Hojjat Derakhshanfar, Afshin Amini, Bahareh Esmailzadeh   +5 more
doaj   +1 more source

Early Open-Lung Ventilation Improves Clinical Outcomes in Patients with Left Cardiac Dysfunction Undergoing Off-Pump Coronary Artery Bypass: a Randomized Controlled Trial

Brazilian Journal of Cardiovascular Surgery
Objective: To compare pulmonary function, functional capacity and clinical outcomes amongst three groups of patients with left ventricular dysfunction following off-pump coronary artery bypass, namely: 1) conventional mechanical ventilation (CMV); 2 ...
Douglas W. Bolzan, Walter José Gomes, Isadora S. Rocco, Marcela Viceconte, Mara L. S. Nasrala, Hayanne O. Pauletti, Rita Simone L. Moreira, Nelson A. Hossne Jr, Ross Arena, Solange Guizilini   +9 more
doaj   +1 more source

Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Oman Medical Journal, 2023
Objectives: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.
Abdul Hakeem Al Hashim, Ibrahim Al Zakwani, Abdullah Al Jadidi, Ruqaiya Al Harthi, Maadh Al Naabi, Ramakrishna Biyappu, Sonali Kodange, Naveen Kumar Asati, Tamadher Al Barhi, Mudhun Mohan, Jayachandiran Jagadeesan, Micheline Sachez, Praisemabel S. Sycaayao, Khalfan Al Amrani, Huda Al Khalili, Rashid Al Mamari, Mujahid Al-Busaidi   +16 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat

Nihon Kikai Gakkai ronbunshu, 2018
We describe a method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat. We have proposed a measurement method of lying posture, respiration, and heartbeat using a Smart Rubber sensor, a rubber ...
Kazuya MATSUO, Toshiharu MUKAI, Shijie GUO   +2 more
doaj   +1 more source