Results 61 to 70 of about 315,034 (346)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Automatic skin flash optimization in breast and chestwall VMAT with static angle modulated ports: Effect of HU and flash margin size on plan quality and robustness

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Skin flash is typically added to breast and chestwall plans to ensure robust target coverage in the presence of respiratory motion, anatomic changes, and small setup uncertainties. Adding skin flash in volumetric modulated arc therapy (VMAT) plans is an iterative and manual process.
Emily Hubley, Brandon Koger, Taoran Li, Michael Salerno, Ryan M. Scheuermann, Lei Dong, Boon‐Keng Kevin Teo   +6 more
wiley   +1 more source

Flow 2.0 -a flexible, scalable, cross-platform post-processing software for realtime phase contrast sequences [PDF]

arXiv, 2022
Flow 2.0 is an end-to-end easy-of-use software that allows us to quickly, robustly and accurately perform a batch process real-time phase contrast data and multivariate analysis of the effect of respiration on cerebral fluids circulation. Synopsis (99/100) Real-time phase contrast sequences (RT-PC) have potential value as a scientific and clinical tool
arxiv  

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu, Krish Shah, Cristina D. Toedebusch, Ashley Hess, Rachel Richardson, Emmanuel Mignot, Suzanne E. Schindler, Tammie L. S. Benzinger, Shaney Flores, Jason Hassenstab, Chengjie Xiong, John C. Morris, David M. Holtzman, Brendan P. Lucey   +13 more
wiley   +1 more source

Repercussões da hiperinsuflação manual em recém-nascidos pré-termo sob ventilação mecânica

Revista Brasileira de Terapia Intensiva
RESUMO Objetivo: Avaliar as repercussões da hiperinsuflação manual, realizada com ressuscitador manual com e sem válvula de pressão positiva expiratória final, sobre a função respiratória de recém-nascidos pré-termo em ventilação mecânica.
Camila Chaves Viana, Carla Marques Nicolau, Regina Celia Turola Passos Juliani, Werther Brunow de Carvalho, Vera Lucia Jornada Krebs   +4 more
doaj   +1 more source

The effects of anesthesia induction and positive pressure ventilation on right-ventricular function: an echocardiography-based prospective observational study

BMC Anesthesiology, 2019
Background General anesthesia induction with the initiation of positive pressure ventilation creates a vulnerable phase for patients. The impact of positive intrathoracic pressure on cardiac performance has been studied but remains controversial.
Harry Magunia, Anne Jordanow, Marius Keller, Peter Rosenberger, Martina Nowak-Machen   +4 more
doaj   +1 more source

Transport of aerosols and nanoparticles through respirators and masks [PDF]

arXiv, 2022
In several countries wearing multiple surgical masks or N95 respirators was mandatory in public during the COVID pandemic. In this study, we investigated the transportation and filtering mechanism of heterogeneous nanoparticles and viruses through surgical masks and N95 respirators.
arxiv  

Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn, Lindsay N. Alfano, Aileen Jones, Amanda Butler, Linda P. Lowes, Megan A. Iammarino, Natalie F. Reash, Lindsay Pietruszewski, Sandhya Sasidharan, Melissa Currence, Jeffrey M. Statland, Talia Strahler, Robert Will, Matthew Wicklund, Stacy Dixon, Renee Augsburger, Tahseen Mozaffar, Katie M. Laubscher, Shelley R. H. Mockler, Katherine D. Mathews, Nikia Stinson, Doris G. Leung, Molly M. Stark, Rebecca A. Horton, Peter B. Kang, Meredith K. James, Amanda Clause, Conrad C. Weihl, Nicholas E. Johnson, GRASP‐LGMD Consortium   +29 more
wiley   +1 more source

Sleep Apnea and Aortic Dissection

Canadian Respiratory Journal, 1995
A 62-year-old man presented with obstructive sleep apnea, congestive heart failure and Cheyne-Stokes respiration. Further evaluation revealed a chronic dissecting aneurysm of the aorta causing vena caval obstruction.
Patrick J Hanly, David Ford
doaj   +1 more source

Influence of expiratory positive airway pressure on cardiac autonomic modulation at rest and in submaximal exercise in COPD patients

Brazilian Journal of Medical and Biological Research, 2018
The aim of this study was to evaluate the effect of expiratory positive airway pressure (EPAP) on heart rate variability (HRV) indices at rest and during 6-min walk test (6MWT) in chronic obstructive pulmonary disease (COPD) patients. Fifteen moderate to
C. da L. Goulart, E.A. San Martin, K.M.K. Mansour, P.B. Schneiders, A.L.G. da Silva   +4 more
doaj   +1 more source