Results 191 to 200 of about 9,419,615 (268)

How do theme park attributes influence visitors' positive emotions? Nonlinear effects and spatial heterogeneity in Shanghai's theme parks. [PDF]

PLoS One
Guo X, Li X, Ren G, Gao M, Han C.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Driving HCV Elimination Through Dedicated Hospital-Based Teams and Pathways: A Retrospective and Prospective Study. [PDF]

Liver Int
Torre P, Serretiello E, Di Siervi G, Vaccaro E, Sarcina T, Festa M, Folliero V, Masarone M, Franci G, Persico M.   +9 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effects of Affect and Source on Adoption of Health Information. [PDF]

Psych J
Shi R, Chen Z, Shang J.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A High Sensitive Detection of Droplet Digital PCR for the Diagnosis of Pulmonary Tuberculosis. [PDF]

Infect Drug Resist
Yang S, Huang M, Xiong Y, Tu C, Xu Y, Wan K, Chen X, Zhang F, Liao X, Chen Q, Zhang J, Liu J.   +11 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Detection of recurrence of HPV-driven oropharyngeal cancer by HPV cell-free DNA. [PDF]

Sci Rep
Fricke NM, Guarda V, Höfler D, Waterboer T, Schouten CS, Ikenberg K, Schroeder L, Rosing F, Broglie Daeppen MA.   +8 more
europepmc   +1 more source

A position on position statements.

The Canadian veterinary journal = La revue veterinaire canadienne
openaire   +2 more sources