Residential mobility, self-concept, and positive affect in social interactions. [PDF]
Shigehiro Oishi+2 more
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Mapping the Neural Basis of Wake Onset Regularity and Its Effects on Sleep Quality and Positive Affect. [PDF]
Negelspach D+5 more
europepmc +1 more source
Positive affect and suicide ideation in older adult primary care patients. [PDF]
Jameson K. Hirsch+3 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Dampening of positive affect partially accounts for the association between women's history of child maltreatment and current depressive symptoms. [PDF]
Stone LB, Sylvester A.
europepmc +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Influence of Gender Role on Resilience and Positive Affect in Female Nursing Students: A Cross-Sectional Study. [PDF]
Mayor-Silva LI+6 more
europepmc +1 more source
Prefrontal Glutathione Levels in Major Depressive Disorder Are Linked to a Lack of Positive Affect. [PDF]
Tuura RO+6 more
europepmc +1 more source