Results 71 to 80 of about 6,360,215 (357)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

A nod in the wrong direction : Does nonverbal feedback affect eyewitness confidence in interviews? [PDF]

open access: yes, 2013
Eyewitnesses can be influenced by an interviewer's behaviour and report information with inflated confidence as a result. Previous research has shown that positive feedback administered verbally can affect the confidence attributed to testimony, but the ...
Daniel J. Gurney   +7 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Measuring Gratitude: A Comparative Validation of the Dutch Gratitude Questionnaire (GQ6) and Short Gratitude, Resentment, and Appreciation Test (SGRAT)

open access: yesPsychologica Belgica, 2015
The aim of this article was to validate and compare the Dutch translations of the Gratitude Questionnaire (GQ6) and the Short Gratitude, Resentment, and Appreciation Test (SGRAT) in an adult general population sample. In an online survey, 706 respondents
Lilian Jans-Beken   +3 more
doaj   +1 more source

Emotional intelligence and satisfaction at work in teachers: Testing affectivity as potential mediator. [PDF]

open access: yes, 2015
Introduction: Although previous research has highlighted the role of emotional intelligence on satisfaction at work, the underlying processes accounting for this association remain relatively unexplored.
Extremera, Natalio   +2 more
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Emotion regulation strategies and aggression in youngsters: The mediating role of negative affect

open access: yesHeliyon, 2023
Aggression in youngsters is a highly prevalent problem worldwide. Given that this problem has negative consequences for society, aggressors, and victims, the present study aims to understand the processes underlying the acts of aggression in this ...
María José Gutiérrez-Cobo   +4 more
doaj  

Affects as Mediators of the Negative Effects of Discrimination on Psychological Well-Being in the Migrant Population

open access: yesFrontiers in Psychology, 2020
There is abundant empirical evidence on the negative effects of discrimination on psychological well-being. However, little research has focused on exploring the factors that can mitigate this effect. Within this framework, the present study examined the
Alfonso Urzúa   +2 more
doaj   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

The Multidimensional Perfectionism Cognitions Inventory–English (MPCI-E): Reliability, validity, and relationships with positive and negative affect [PDF]

open access: yes, 2010
The Multidimensional Perfectionism Cognitions Inventory (MPCI; Kobori & Tanno, 2004) is a promising new instrument developed in Japan to assess perfectionism cognitions regarding personal standards, pursuit of perfection, and concern over mistakes.
Kobori, Osamu   +2 more
core   +1 more source

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