Results 71 to 80 of about 7,757,969 (275)

The influence of Adverse and Positive Childhood Experiences on facets of empathy

Child Abuse & Neglect
Although Adverse Childhood Experiences (ACEs) have been associated with empathy, research findings have been incongruous. In contrast, positive parenting practices have been consistently, and positively, associated with empathy.The current study investigated whether the relationship between ACEs and facets of empathy (i.e., perspective taking, empathic
George Van Doorn, Jacob Dye, Robert Teese   +2 more
openaire   +2 more sources

Relationship between childhood socioeconomic position and adverse childhood experiences (ACEs): a systematic review [PDF]

Journal of Epidemiology and Community Health, 2019
Background ‘Adverse childhood experiences’ (ACEs) are associated with increased risk of negative outcomes in later life: ACEs have consequently become a policy priority in many countries. Despite ACEs being highly socially patterned, there has been very little discussion in the political discourse regarding the role
David Walsh, Gerry McCartney, Michael Smith, Gillian Armour   +3 more
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Positive childhood experiences and organizational identity perceptions of preschool teachers

, 2022
Bu çalışmanın amacı, okul öncesi öğretmenlerinin çocukluk çağı olumlu yaşantıları ile örgütsel kimlik algıları arasındaki ilişkinin incelenmesidir. İlişkisel tarama modelinde tasarlanan araştırmaya 2020-21 eğitim öğretim yılında resmi ve özel okul öncesi
POLAT, ÖZGÜL
core   +1 more source

Negative effects of adverse childhood experiences and absence of positive childhood experiences on healthcare employees: survey findings built on 10 years of trauma-informed development

Frontiers in Public Health
IntroductionExisting data on how history of trauma and adversity affects healthcare professionals is limited. This study sought to describe the prevalence of Adverse Childhood Experiences (ACEs) and Positive Childhood Experiences (PCEs) and their ...
Laneita Williamson, Laneita Williamson, Stephanie S. Daniel, Jennifer Carter, Adam Ridenhour, Camila A. Pulgar, Yasmin Gay, Beata Debinski   +7 more
doaj   +1 more source

Structural Equation Modeling of Self-Control Based on Positive Childhood Experiences with the Mediating Role of Self-Compassion in Substance-Dependent Individuals [PDF]

پژوهشنامه روانشناسی مثبت
The aim of the present study was to investigate the positive relationship between positive childhood experiences and self-regulation in individuals with substance dependence undergoing methadone maintenance treatment and to determine the mediating role ...
Narjes Ameri, Mahmood Najafi
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source