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Ethical Perspectives of Equal Opportunities [PDF]
This paper focuses on the analysis of the fair equality of the concept of opportunity from the perspective of the moral and reasonable justifications brought to support positive discrimination.
Traian PALADE
doaj
Research on how autistic people are perceived by neurotypical people indicates that disclosing a diagnosis leads to a positive discriminatory bias; however, autobiographical autistic accounts indicate that diagnostic disclosure often results in negative ...
Brett Heasman, Alex Gillespie
doaj +1 more source
On mixed discriminants of positively definite matrix
In the paper, some new inequalities for the mixed discriminants of positively definite matrix are established, which are the matrix analogues of inequalities of the well-known mixed volumes function.
Li, Xiao-Yan, Zhao, Chang-Jian
openaire +3 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The purpose of this article is to consider the trans-historic dimension of the discussions around positive discrimination in France with the aim to emphasize the origins and continuities of the phenomenon.
Karim Ghorbal
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Diversity in the British police : adapting to a multicultural society
Historically white male dominated, the police service was criticised for having a sexist and racist culture and lacking black, Asian and female officers.
Bela Bhugowandeen
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

