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Ethical Perspectives of Equal Opportunities [PDF]

open access: yesAnnals of Philosophy, Social and Human Disciplines, 2016
This paper focuses on the analysis of the fair equality of the concept of opportunity from the perspective of the moral and reasonable justifications brought to support positive discrimination.
Traian PALADE
doaj  

Participants Over-Estimate How Helpful They Are in a Two-Player Game Scenario Toward an Artificial Confederate That Discloses a Diagnosis of Autism

open access: yesFrontiers in Psychology, 2019
Research on how autistic people are perceived by neurotypical people indicates that disclosing a diagnosis leads to a positive discriminatory bias; however, autobiographical autistic accounts indicate that diagnostic disclosure often results in negative ...
Brett Heasman, Alex Gillespie
doaj   +1 more source

On mixed discriminants of positively definite matrix

open access: yesArs Mathematica Contemporanea, 2015
In the paper, some new inequalities for the mixed discriminants of positively definite matrix are established, which are the matrix analogues of inequalities of the well-known mixed volumes function.
Li, Xiao-Yan, Zhao, Chang-Jian
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Colonial Essence of a Contemporary Policy: Towards a Fanonian Approach of Positive Discrimination in France

open access: yesCulture & History Digital Journal, 2015
The purpose of this article is to consider the trans-historic dimension of the discussions around positive discrimination in France with the aim to emphasize the origins and continuities of the phenomenon.
Karim Ghorbal
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Diversity in the British police : adapting to a multicultural society

open access: yesCahiers du MIMMOC, 2013
Historically white male dominated, the police service was criticised for having a sexist and racist culture and lacking black, Asian and female officers.
Bela Bhugowandeen
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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