Results 151 to 160 of about 25,228,093 (291)

The PERMA - profiler: psychometrics properties among teachers

مجله علوم روانشناختی, 2019
Background: Martin M Seligman has developed a multi-dimensional model of Flourishing, PERMA. This model combines positive emotion (hedonic) and positive performance (eudiamonic) dimensions.
Mohammad Hossein Sahrifian, Jalil Fath abadi, Omid Shokri, Saeed Ghanbari   +3 more
doaj  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

State Plan for Fiscal Year ... Vocational Education. Vocational education in Kansas: state plan (1960)

, 1960
1960 and 1964 editions were issued by State Board for Vocational ...
Kansas. Division of Vocational Education
core  

Nature-Positive Solutions and CGIAR: A pop up exhibit

Nature-Positive Solutions and CGIAR is a pop-up art exhibition featuring information artworks produced in collaboration with The Lexicon of Sustainability and the CGIAR Nature-Positive Solutions Initiative.
CGIAR Nature-Positive Solutions Initiative, Lexicon of Sustainability   +1 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Doing the right thing and doing things right: secondary school students’ perspectives on a school-based intervention to promote mental well-being

Frontiers in Education
Well-being interventions are often designed and delivered based on external assumptions rather than students’ perspectives, creating a research-practice gap that risks undermining their acceptability.
Lena Uvhagen, Fredrik Söderqvist, Johanna Gustafsson   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

POSITIVE EDUCATION: INCORPORATING POSITIVE PSYCHOLOGY INTO THE CLASSROOM FOR STUDENTS’ ACADEMIC SUCCESS

Shodh Sari
In recent years, there has been a paradigm shift in education towards a more holistic approach through incorporating positive psychology to support student’s academic success and well-being. This piece thoroughly analyses the notion of positive education
Dr. Ruth Moniloye Oyeniyi
doaj   +1 more source