Results 181 to 190 of about 25,228,093 (291)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A positive approach to business ethics education

, 2016
Business students are not effectively learning to become ethical business managers. Prevailing business ethical educational pedagogies are negative, unattractive, inconsistent, confusing and counterproductive.
Hillard, Jeffrey L.
core  

Why won't it Stick? Positive Psychology and Positive Education. [PDF]

Psychol Well Being, 2016
White MA.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Editorial: Positive Psychology in Everyday Life

Frontiers in Psychology, 2022
Margarida Pocinho, Margarida Pocinho, Soraia Garcês, Soraia Garcês, Daniela Popa   +4 more
doaj   +1 more source

Enhancing mental well-being in university students through multicomponent low intensity positive education and the mediating role of civic engagement. [PDF]

Sci Rep
Ng TY, Ng TK, Siu OL.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Erratum to: Scaling-up an efficacious school-based physical activity intervention: Study protocol for the ‘Internet-based Professional Learning to help teachers support Activity in Youth’ (iPLAY) cluster randomized controlled trial and scale-up implementation evaluation

BMC Public Health, 2016
Chris Lonsdale, Taren Sanders, Kristen E. Cohen, Philip Parker, Michael Noetel, Tim Hartwig, Diego Vasconcellos, Morwenna Kirwan, Philip Morgan, Jo Salmon, Marj Moodie, Heather McKay, Andrew Bennie, Ron Plotnikoff, Renata L. Cinelli, David Greene, Louisa R. Peralta, Dylan P. Cliff, Gregory S. Kolt, Jennifer M. Gore, Lan Gao, David R. Lubans   +21 more
doaj   +1 more source

Using social media-based positive education to challenge negative stereotypes of aging: a quasi-experimental approach. [PDF]

BMC Public Health
Fuente-Hernández L, de la Fuente-Ruiz E, Gracia-García P, Serrano-García I, Álvarez-Mon MÁ, Molina-Ruiz RM.   +5 more
europepmc   +1 more source