Results 91 to 100 of about 9,753,657 (384)

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Effects of Smartphone-Delivered Positive-Word Stimulation on Depressed Mood in People with Subthreshold Depression: Protocol for a Pilot Randomized Controlled Trial [Corrigendum]

Neuropsychiatric Disease and Treatment, 2021
Ejiri H, Uchida H, Tsuchiya K, Fujiwara K, Kikuchi S, Hirao K. Neuropsychiatr Dis Treat. 2021;17:2739–2748. Page 2739, Abstract, Trial Registration, the text “NCT03864484” should read “NCT04707495”. The authors apologize for
Ejiri H, Uchida H, Tsuchiya K, Fujiwara K, Kikuchi S, Hirao K   +5 more
doaj  

Peer mentorship and positive effects on student mentor and mentee retention and academic success [PDF]

, 2012
This study examined how the introduction of peer mentorship in an undergraduate health and social welfare programme at a large northern university affected student learning.
A. Bandura, A. Bandura, A. Roberts, B. Glaser, B. Glaser, C. Stringer-Cawyer, D. Robotham, G. Alred, H. Margolis, H. Piper, J. Lave, J. Lennox-Terrion, J. Terrion-Lennox, L. Breen, L. L. Paglis, L. Reisberg, M. Jacobi, M. McLean, N. M. Drew, R Abouserie, R. Misra, S. Flumerfeldt, S. Rodger, T. A. Campbell   +23 more
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Learning from Positive and Unlabeled Data with Arbitrary Positive Shift [PDF]

arXiv, 2020
Positive-unlabeled (PU) learning trains a binary classifier using only positive and unlabeled data. A common simplifying assumption is that the positive data is representative of the target positive class. This assumption rarely holds in practice due to temporal drift, domain shift, and/or adversarial manipulation.
arxiv  

On the positive effects of taxation on education [PDF]

In the economic literature a constant tax rate on labor income has usually a neutral or negative effect on education. The effect is neutral in the absence of non-deductible costs and it is negative in the presence of them.
Lari Arthur Viianto
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Inverse-Positive Matrices and Stability Properties of Linear Stochastic Difference Equations with Aftereffect

Mathematics
This article examines the stability properties of linear stochastic difference equations with delays. For this purpose, a novel approach is used that combines the theory of inverse-positive matrices and the asymptotic methods developed by N.V.
Arcady Ponosov, Ramazan I. Kadiev
doaj   +1 more source

Positive and normative effects of a minimum wage [PDF]

We review the positive and normative effects of a minimum wage in various versions of a search-theoretic model of the labor market.Minimum wage ; Labor ...
Guillaume Rocheteau, Murat Tasci
core  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source