Results 151 to 160 of about 3,784,145 (318)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Clinical, serologic, and immunologic effects of human leukocyte interferon in HBsAg-positive primary hepatocellular carcinoma [PDF]

, 1985
Prem V. Nair, Myron J. Tong, Raymond A. Kempf, Ruth L. Co, Shou‐Dong Lee, Cheryl L. Venturi   +5 more
openalex   +1 more source

Effects of Continuous Positive Airway Pressure on Cognition and Neuroimaging Biomarkers In Obstructive Sleep Apnoea: A Multicentre Randomised Controlled Trial

, 2023
Huajun Xu, Yupu Liu, Chenyang Li, Xinyi Li, Li Shen, Hui Wang, Feng Liu, Juanjuan Zou, Yunyan Xia, Weijun Huang, Yuenan Liu, Zhenfei Gao, Yiqun Fu, Fan Wang, Shujian Huang, Zhiyuan Song, S. Fan, Yiqing Gao, Yu Peng, Jianyin Zou, Huaming Zhu, Suru Liu, Linpeng Li, Xiaoyue Zhu, Yuanping Xiong, Yuli Hu, Jiaxin Yang, Yuehua Li, Feng Gao, Qihao Guo, Hengye Huang, Weituo Zhang, Jiping Li, Yanqing Chen, Pin Dong, Jun Yang, Jingrong Lv, Peihua Wang, Yiyuan Sun, Biyun Qian, Kristine Yaffe, Hongliang Yi, Jian Guan, Yue Leng, Shankai Yin   +44 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Positive Effects of Nutritional Education in a Patient With Pleuroparenchymal Fibroelastosis. [PDF]

Cureus
Yamakawa H, Ohta H, Sato S, Matsushima H.   +3 more
europepmc   +1 more source

SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability

, 2011
Glenn M. Marshall, Pei Y. Liu, Samuele Gherardi, Christopher J. Scarlett, Antonio Bedalov, Ning Xu, Nunzio Iraci, Emanuele Valli, Dora Ling, Wayne Thomas, M. van der Starre-van Bekkum, Eric Sekyere, Kacper Jankowski, Toby N. Trahair, Karen L. MacKenzie, Michelle Haber, Murray D. Norris, Andrew V. Biankin, Giovanni Perini, Tao Liu   +19 more
openalex   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The Design and Impact of Teaching Kitchens and Hands-On Cooking Strategies on Diverse Populations: Increasing Evidence of Positive Effects and Proposed Future Directions. [PDF]

Nutrients
Eisenberg DM, Cole A, Pacheco LS, Massa J, Haramati A, Bremer AA.   +5 more
europepmc   +1 more source

Just a small bunch of flowers: the botanical knowledge of students and the positive effects of courses in plant identification at German universities

, 2019
Thorsten Buck, Ines Bruchmann, Pascale Zumstein, Claudia Drees   +3 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source