Results 181 to 190 of about 4,124,077 (217)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

The Positive Effects of Training and Time-Restricted Eating in Gut Microbiota Biodiversity in Patients with Multiple Myeloma. [PDF]

Nutrients
Czerwińska-Ledwig O, Nowak-Zaleska A, Żychowska M, Meyza K, Pałka T, Dzidek A, Szlachetka A, Jurczyszyn A, Piotrowska A.   +8 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Short-term WB-EMS in Cancer Patients: Positive Effects After 2 Weeks of Exercise-A Single-arm Trial. [PDF]

Integr Cancer Ther
Kersten J, Niels T, Tomanek A, Baumann FT.   +3 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Investigation of Possible Positive Effects of Arbutin Application in Experimental Colitis Model. [PDF]

Turk J Gastroenterol
Alemdar MB, Şirinyıldız F, Coşkun A, Meteoğlu İ, Taşkıran İ, Kandemir A, Yaşa MH.   +6 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance. [PDF]

J Neurosci
Cintado E, Tezanos P, De Las Casas M, Muela P, McGreevy KR, Fontán-Lozano Á, Sacristán-Horcajada E, Pignatelli J, de Ceballos ML, Del Hierro MJ, Fernández-Punzano J, Montoliu L, Trejo JL.   +12 more
europepmc   +1 more source

Positive effects of forest fragmentation <i>per se</i> on bryophyte diversity in subtropical fragmented forests: evidence from land-bridge islands. [PDF]

Front Plant Sci
Li D, Yuan T, Yang J, Lv S, Zhang H, Xia Y, Wang X, Guo S, Yu J.   +8 more
europepmc   +1 more source

The BASIDIN effector of the fungus Moniliophthora perniciosa promotes positive effects on the seed germination and seedlings development of Lactuca sativa. [PDF]

Front Plant Sci
Farias KS, Ferreira MM, De Oliveira IB, Dalio RJD, Pirovani CP.   +4 more
europepmc   +1 more source