Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Positive effects of audit and feedback on antimicrobial use in hospitalized patients limited to audited patients. [PDF]
Engel-Dettmers EM +5 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Age-Related Brain Atrophy and the Positive Effects of Behavioral Enrichment in Middle-Aged Beagles. [PDF]
Noche JA +18 more
europepmc +1 more source
Positive Effects of Guanidinium Salt Post-Treatment on Multi-Cation Mixed Halide Perovskite Solar Cells. [PDF]
Aidarkhanov D +6 more
europepmc +1 more source
Positive Effects of a Resveratrol-Based Nutraceutical in Association with Surgical Scleroembolization: A Pilot Retrospective Clinical Trial. [PDF]
Italiano E +5 more
europepmc +1 more source
Effects of Positive Verbal Reinforcement on the Four Underlying Factors in Intrinsic Motivation
Ray Prentice
openalex +1 more source
Positive effects of public breeding on US rice yields under future climate scenarios. [PDF]
Wang DR +5 more
europepmc +1 more source
Positive effects and mechanism of mulberry leaf extract on alleviating fatty liver hemorrhagic syndrome in laying hens. [PDF]
Zhang W +6 more
europepmc +1 more source

