Results 51 to 60 of about 4,124,077 (217)
CHIMIA, 2003 The stereoselectivity of the formation of bis-chelates with the 1,9-disubstituted chiral semicorrin ligands (1S,9S)-dimethyl 5-cyanosemicorrin-1,9-dicarboxylate (1) for Co2+, Ni2+, Cu2+, and Pd2+ and with its (1S,9S)-diethyl analogue 2 for Co2+
Nathalie Guicher +2 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Armaghane Danesh Bimonthly Journal, 2021 Background & aim: Currently, with increasing resistance to synthetic drugs, the demand for natural and safe alternatives to these types of medications has increased. Therefore, the aim of the present study was to determine and evaluate the antibacterial
J Sayyahi +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Psychiatry and Clinical Psychopharmacology, 2021 Objective: In this study, we aimed if there is an effect of smoking upon the treatment response of antipsychotics and side effects of drugs in the acutely hospitalized chronic schizophrenic patients. Method: Fourty five patients in patients, diagnosed
Çiğdem Demir +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BMC BioinformaticsBackground This study highlights biologically meaningless negative contributions to heritability estimates and introduces SAFE-h 2 method and application tool for accurate genetic estimates in genome-wide association studies.
Behrooz Darbani, Mogens Nicolaisen
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Partial Stability of Linear Hybrid Discrete–Continuous Itô Systems with Aftereffect
MathematicsThis paper offers several new sufficient conditions of the partial moment stability of linear hybrid stochastic systems with delay. Despite its potential applications in economics, biology and physics, this problem seems to have not been addressed before.
Ramazan I. Kadiev, Arcady Ponosov
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
NITROGEN CYCLE IN NATURE: POSITIVE AND NEGATIVE EFFECTS [PDF]
Vestnik Issyk-Kulʹskogo universitetaThis study examines the process of nitrogen cycling in nature, as well as its positive and negative effects on ecosystems. Nitrogen is one of the most common elements in nature, is part of the main biological compounds and is one of the most important ...
Beknazarova Zh. M.
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